Starch to protein ratio and food moisture content influence water balance and urine supersaturation in cats.

Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Original Publication: San Francisco, CA : Public Library of Science

Starch*/metabolism ; Water*/chemistry ; Dietary Proteins*/analysis ; Dietary Proteins*/urine; Animals ; Cats ; Animal Feed/analysis ; Calcium/urine ; Calcium/analysis ; Urine/chemistry ; Male ; Calcium Oxalate/urine ; Phosphates/urine ; Phosphates/analysis ; Magnesium Compounds/urine ; Diet/veterinary ; Struvite ; Female

Competing Interests: The authors have declared that no competing interests exist.
Two starch to protein ratios (high starch [HS], 25% starch and 36% protein; high protein [HP], 15% starch and 53% protein on DM basis) and two moisture contents (5%, dry kibbles; 80%, wet food) were compared in a 2 x 2 factorial arrangement totaling 4 diets. Each diet was evaluated in 9 cats, with 8 d of total collection of urine and feces. Results were subjected to an analysis of variance of the effects of starch to protein ratio, moisture content and their interactions (P<0.05). Urine density was lower and volume was higher in cats fed wet foods (P<0.01). Calcium (Ca) urine concentration was higher for dry and HP diets (P<0.05). The oxalate urine concentration was 60% higher for cats fed both HS formulations (dry and wet; P<0.05). The relative supersaturation (RSS) of urine for calcium oxalate was higher for dry foods and HS formulations (P<0.01), and for struvite, it was lower for both wet foods, and among the dry diets, it was lower for the HS than for the HP formulation (P<0.01). Foods with a high protein-to-starch ratio reduced urine oxalate and RSS for calcium oxalate in wet and dry diets, and wet foods reduced RSS for calcium oxalate and struvite.
(Copyright: © 2024 Gonçalves Tozato et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

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9005-25-8 (Starch)
059QF0KO0R (Water)
0 (Dietary Proteins)
SY7Q814VUP (Calcium)
2612HC57YE (Calcium Oxalate)
0 (Phosphates)
0 (Magnesium Compounds)
AW3EJL1462 (Struvite)

Date Created: 20241218 Date Completed: 20241218 Latest Revision: 20250104

20250114

PMC11654968

10.1371/journal.pone.0315949

39693372