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Design of hydrated porphyrin-phospholipid bilayers with enhanced magnetic resonance contrast

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  • Additional Information
    • Publication Date:
      2017
    • Abstract:
      Computer simulations are used to design more hydrated bilayers, formed from amine-modified porphyrin-phospholipids (PoPs). Experiments confirm that the new constructs give rise to bilayers with greater water content. When chelated with manganese, amine-modified PoPs provide improved contrast for magnetic resonance and are safely used for imaging in vivo
    • Accession Number:
      10.1002/smll.201602505
    • Online Access:
      https://research.tue.nl/en/publications/b88bbc8f-861a-44f0-89f2-dd544d4adb5e
      https://doi.org/10.1002/smll.201602505
      http://www.scopus.com/inward/record.url?scp=84991628541&partnerID=8YFLogxK
    • Rights:
      info:eu-repo/semantics/openAccess
    • Accession Number:
      edsbas.B3BF1B29