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Project profile: a multicenter study on breast cancer in young women in Latin America (PRECAMA study).

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  • Additional Information
    • Transliterated Title:
      Perfil de Proyecto: Un estudio multicéntrico sobre el cáncer de mama en mujeres jóvenes en América Latina (estudio PRECAMA).
    • Corporate Authors:
    • Source:
      Publisher: Instituto Nacional de Salud Pública Country of Publication: Mexico NLM ID: 0404371 Publication Model: Print Cited Medium: Internet ISSN: 1606-7916 (Electronic) Linking ISSN: 00363634 NLM ISO Abbreviation: Salud Publica Mex Subsets: MEDLINE
    • Publication Information:
      Publication: Mexico : Instituto Nacional de Salud Pública
      Original Publication: [México] : La Secretaría, [1959-
    • Subject Terms:
    • Abstract:
      Objective: To describe the rationale and the methodology of a multicenter project to study the etiology of breast cancer in young Latin American women.
      Materials and Methods: The International Agency for Research on Cancer has established an international collaborative population-based case-control study in four countries in Latin America: Chile, Colombia, Costa Rica, and Mexico (the PRECAMA study). Standardized methodologies were developed to collect information on reproductive variables, lifestyle, anthropometry, diet, clinical and pathological data, and biological specimens. The study will be extended to other countries in the region.
      Conclusions: PRECAMA is unique in its multidisciplinary approach that combines genetics, genomics, and metabolomics with lifestyle factors. Then data generated through this project will be instrumental to identify major risk factors for molecular subtypes of breast cancer in young women, which will be important for pre- vention and targeted screening programs in Latin America.
      Competing Interests: Declaration of conflict of interests. The authors declare that they have no conflict of interests.
    • Grant Information:
      001 International WHO_ World Health Organization
    • Contributed Indexing:
      Investigator: C Biessy; M Olivier; S Rinaldi; I Romieu; ML Garmendia; JL Soto; E Bustamante; L Moyano; A Angel; CA Ossa; WH Arias; G Bedoya; M Borrero; A Cock-Rada; I Díaz-Yúnez; C Echeverri; F Herazo; Á Hernández; R Jaramillo; E Navarro; Y Rodas Cortés; GI Sánchez; B Cortés; P González; D Guillén; V Loría; R Ocampo; C Porras; AC Rodríguez; G Torres-Mejía; I Alvarado-Cabrero; A Ángeles-Llerenas; J Tejeda; P Porter
      Keywords: Latin America; breast cancer; risk factors; women
      Local Abstract: [Publisher, Spanish; Castilian] Describir la justificación y la metodología para el establecimiento de un proyecto multicéntrico sobre el cáncer de mama en mujeres jóvenes de América Latina. [Publisher, Spanish; Castilian] La Agencia Internacional para la Investigación del Cáncer (IARC) ha establecido un estudio colaborativo internacional de casos y controles con base poblacional en cuatro países de América Latina: Chile, Colombia, Costa Rica y México (el estudio PRECAMA). Se han desarrollado metodologías estandarizadas para recolectar información sobre variables reproductivas, estilos de vida, antropometría y dieta, datos clínicos y patológicos y muestras biológicas. [Publisher, Spanish; Castilian] PRECAMA es único en su enfoque multidisciplinario. Los datos generados a través de este proyecto serán fundamentales para identificar los principales factores de riesgo del cáncer de mama en mujeres jóvenes. Los hallazgos serán relevantes para la prevención y los programas de detección oportuna en América Latina, con beneficios clínicos inmediatos.
    • Publication Date:
      Date Created: 20191030 Date Completed: 20200424 Latest Revision: 20240324
    • Publication Date:
      20240324
    • Accession Number:
      10.21149/10466
    • Accession Number:
      31661737