Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read Online Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE
    • Publication Information:
      Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-
    • Subject Terms:
      Vaccinia virus*/immunology; Communicable Diseases, Emerging/*epidemiology ; Communicable Diseases, Emerging/*virology ; Vaccinia/*epidemiology ; Vaccinia/*virology ; Zoonoses/*epidemiology; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Agriculture ; Animals ; Child ; Colombia/epidemiology ; Female ; Humans ; Immunoglobulin G/immunology ; Immunoglobulin M/immunology ; Male ; Middle Aged ; Orthopoxvirus/immunology ; Risk Factors ; Seroepidemiologic Studies ; Young Adult
    • Abstract:
      In 2014, vaccinia virus (VACV) infections were identified among farmworkers in Caquetá Department, Colombia; additional cases were identified in Cundinamarca Department in 2015. VACV, an orthopoxvirus (OPXV) used in the smallpox vaccine, has caused sporadic bovine and human outbreaks in countries such as Brazil and India. In response to the emergence of this disease in Colombia, we surveyed and collected blood from 134 farmworkers and household members from 56 farms in Cundinamarca Department. We tested serum samples for OPXV antibodies and correlated risk factors with seropositivity by using multivariate analyses. Fifty-two percent of farmworkers had OPXV antibodies; this percentage decreased to 31% when we excluded persons who would have been eligible for smallpox vaccination. The major risk factors for seropositivity were municipality, age, smallpox vaccination scar, duration of time working on a farm, and animals having vaccinia-like lesions. This investigation provides evidence for possible emergence of VACV as a zoonosis in South America.
    • References:
      PLoS One. 2009 Oct 19;4(10):e7428. (PMID: 19838293)
      Bol Oficina Sanit Panam. 1967 Aug;63(2):111-21. (PMID: 4233429)
      Emerg Infect Dis. 2015 Apr;21(4):695-8. (PMID: 25811411)
      Emerg Infect Dis. 2017 Apr;23(4):649-653. (PMID: 28322708)
      J Dairy Sci. 2017 Sep;100(9):7051-7054. (PMID: 28734599)
      Emerg Infect Dis. 2015 Dec;21(12):2244-6. (PMID: 26583465)
      Int J Health Geogr. 2017 Aug 7;16(1):28. (PMID: 28784125)
      Emerg Infect Dis. 2003 Feb;9(2):155-60. (PMID: 12603984)
      PLoS One. 2011;6(8):e23086. (PMID: 21858000)
      J Virol. 2015 Dec;89(23):11909-25. (PMID: 26378174)
      Antiviral Res. 2011 Nov;92(2):150-63. (PMID: 21896287)
      Am J Trop Med Hyg. 1967 May;16(3):332-8. (PMID: 6067215)
      Virus Genes. 2001 Dec;23(3):291-301. (PMID: 11778697)
      Emerg Infect Dis. 2005 Dec;11(12):1935-8. (PMID: 16485483)
      Am J Trop Med Hyg. 1965 Jan;14:156-7. (PMID: 14248989)
      Viruses. 2018 Jan 23;10(2):. (PMID: 29360742)
      Arch Virol. 1998;143(6):1171-86. (PMID: 9687874)
      Arch Virol. 2009;154(9):1551-3. (PMID: 19710997)
      PLoS Pathog. 2013;9(12):e1003756. (PMID: 24339772)
      Emerg Infect Dis. 2012 Jan;18(1):189-91. (PMID: 22260819)
      Rev Inst Med Trop Sao Paulo. 2004 Nov-Dec;46(6):315-22. (PMID: 15654477)
      J Clin Microbiol. 2007 Apr;45(4):1370-2. (PMID: 17287326)
      Foodborne Pathog Dis. 2010 Dec;7(12):1491-6. (PMID: 20707725)
      Foodborne Pathog Dis. 2015 Nov;12(11):898-903. (PMID: 26545169)
      Emerg Infect Dis. 2007 Jul;13(7):965-72. (PMID: 18214166)
      Foodborne Pathog Dis. 2009 Nov;6(9):1141-6. (PMID: 19888798)
      Am J Trop Med Hyg. 2006 Sep;75(3):486-90. (PMID: 16968926)
      Virology. 2000 Nov 25;277(2):439-49. (PMID: 11080491)
      Rev Sci Tech. 2006 Dec;25(3):981-7. (PMID: 17361764)
      Clin Diagn Lab Immunol. 2005 Jul;12(7):867-72. (PMID: 16002637)
      Am J Trop Med Hyg. 2008 Nov;79(5):647-51. (PMID: 18981497)
      Arch Virol. 2010 Feb;155(2):255-61. (PMID: 19956986)
      Transbound Emerg Dis. 2018 Feb;65(1):e40-e47. (PMID: 28649801)
      Arch Virol. 2013 Dec;158(12):2433-41. (PMID: 23760628)
      Emerg Infect Dis. 2013 Dec;19(12):2045-7. (PMID: 24274787)
      J Clin Virol. 2009 Apr;44(4):308-13. (PMID: 19243990)
      Vet Microbiol. 2010 Jan 27;140(3-4):229-36. (PMID: 19828265)
      J Gen Virol. 2008 Dec;89(Pt 12):2986-91. (PMID: 19008383)
      J Gen Virol. 2002 Jan;83(Pt 1):223-8. (PMID: 11752719)
    • Contributed Indexing:
      Keywords: Colombia; dairy farms; orthopoxvirus; vaccinia virus; viruses; zoonoses; zoonotic
    • Accession Number:
      0 (Immunoglobulin G)
      0 (Immunoglobulin M)
    • Publication Date:
      Date Created: 20191120 Date Completed: 20200413 Latest Revision: 20200413
    • Publication Date:
      20240104
    • Accession Number:
      PMC6874243
    • Accession Number:
      10.3201/eid2512.181114
    • Accession Number:
      31743085