Prevalencia etiológica de infección del tracto urinario en gestantes sintomáticas, en un hospital de alta complejidad de Medellín, Colombia, 2013-2015

Etiological prevalence of urinary tract infections in symptomatic pregnant women in a high complexity hospital in Medellín, Colombia, 2013-2015

Publisher: Sociedad Colombiana De Obstetricia Y Ginecologia Country of Publication: Colombia NLM ID: 0404263 Publication Model: Print Cited Medium: Internet ISSN: 2463-0225 (Electronic) Linking ISSN: 00347434 NLM ISO Abbreviation: Rev Colomb Obstet Ginecol Subsets: MEDLINE

Publication: Bogota : Sociedad Colombiana De Obstetricia Y Ginecologia
Original Publication: Bogotá [1950?]-

Community-Acquired Infections/*epidemiology ; Pregnancy Complications, Infectious/*epidemiology ; Urinary Tract Infections/*epidemiology; Adult ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/pharmacology ; Bacteria/drug effects ; Bacteria/isolation & purification ; Bacterial Infections/epidemiology ; Bacterial Infections/microbiology ; Colombia/epidemiology ; Community-Acquired Infections/microbiology ; Cross-Sectional Studies ; Drug Resistance, Bacterial ; Female ; Humans ; Pregnancy ; Pregnancy Complications, Infectious/microbiology ; Prevalence ; Urinary Tract Infections/microbiology ; Young Adult

Objective: To determine the prevalence of urinary tract infections (UTIs), the microbiological profile and antibiotic resistance in pregnant women with suspected urinary tract infection.
Materials and Methods: Cross-sectional study of pregnant women with suspected community- acquired urinary tract infection referred to the outpatient clinic by prenatal care practitioners or seen in the emergency room, and hospitalized be- tween August 2013 and September 2015 in a referral teaching hospital located in Medellin, Colombia. Pregnant women who had received antibiotics on the day before admission were excluded. Random sampling. Measured variables: sociodemographic, clinical and bacteriological. Descriptive statistics were applied.
Results: The prevalence of urinary tract infections was 29%. Gram negative bacteria isolates were found predominantly, the main ones being E. coli and K. pneumoniae at 57.7 and 11.4%, respectively. Resistance to trimethoprim- sulfamethoxazole and to ampicillin-sulbactam was observed in 19.5% and 17.5% of isolates, respectively.
Conclusions: Population-based studies are needed to provide a better approach to bacterial resistance in community-acquired UTIs. On the other hand, the high resistance observed may suggest that some of the exposed antibiotics might not be included in the local guidelines for the management of UTIs.
Competing Interests: None declared
(Copyright© 2019 This is an open-access article distributed under the terms of the Creative Commons Attribution License by-nc-nd/4.0.)

Keywords: infectious complications of pregnancy; urinalysis; urinary infections
Local Abstract: [Publisher, Spanish; Castilian] PREVALENCIA ETIOLÓGICA DE INFECCIÓN DEL TRACTO URINARIO EN GESTANTES SINTOMÁTICAS, EN UN HOSPITAL DE ALTA COMPLEJIDAD DE MEDELLÍN, COLOMBIA, 2013-2015. [Publisher, Spanish; Castilian] Determinar la prevalencia de infección del tracto urinario (ITU), el perfil microbiológico y la resistencia a los antibióticos en mujeres gestantes con sospecha de infección del tracto urinario. [Publisher, Spanish; Castilian] Estudio de corte transversal. Ingresaron gestantes con sospecha de infección del tracto urinario adquirida en la comunidad, remitidas a consulta externa desde su control prenatal o atención por urgencias, y hospitalizadas entre agosto de 2013 y septiembre de 2015 en un hospital universitario de referencia ubicado en Medellín, Colombia. Se excluyeron gestantes que hubieran recibido antibióticos el día anterior a la admisión. Muestreo aleatorio simple. Variables medidas: sociodemográficas, clínicas y bacteriológicos. Se aplicó estadística descriptiva. [Publisher, Spanish; Castilian] La prevalencia de infección del tracto urinario fue del 29 %. Predominaron los aislamientos de bacterias Gram negativas, principalmente E. coli y K. pneumoniae en un 57,7 y 11,4 % respectivamente. Se observó resistencia a trimetoprim- sulfametoxazol en el 19,5 % y ampicilina-sulbactam en el 17,5 % de los aislamientos. [Publisher, Spanish; Castilian] Se requieren estudios de base poblacional para una mejor aproximación a la resistencia de las bacterias causantes de la ITU en la comunidad. Por otra parte, la alta resistencia observada podría sugerir que algunos antibióticos expuestos no sean incluidos en las guías locales de manejo de la ITU.

0 (Anti-Bacterial Agents)

Date Created: 20200307 Date Completed: 20200819 Latest Revision: 20240229

20240229

10.18597/rcog.3332

32142239