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Moderate Mocha Coffee Consumption Is Associated with Higher Cognitive and Mood Status in a Non-Demented Elderly Population with Subcortical Ischemic Vascular Disease.

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  • Additional Information
    • Source:
      Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
    • Publication Information:
      Original Publication: Basel, Switzerland : MDPI Publishing
    • Subject Terms:
    • Abstract:
      To date, interest in the role of coffee intake in the occurrence and course of age-related neurological and neuropsychiatric disorders has provided an inconclusive effect. Moreover, no study has evaluated mocha coffee consumption in subjects with mild vascular cognitive impairment and late-onset depression. We assessed the association between different quantities of mocha coffee intake over the last year and cognitive and mood performance in a homogeneous sample of 300 non-demented elderly Italian subjects with subcortical ischemic vascular disease. Mini Mental State Examination (MMSE), Stroop Colour-Word Interference Test (Stroop T), 17-items Hamilton Depression Rating Scalfe (HDRS), Activities of Daily Living (ADL), and Instrumental ADL were the outcome measures. MMSE, HDRS, and Stroop T were independently and significantly associated with coffee consumption, i.e., better scores with increasing intake. At the post-hoc analyses, it was found that the group with a moderate intake (two cups/day) had similar values compared to the heavy drinkers (≥three cups/day), with the exception of MMSE. Daily mocha coffee intake was associated with higher cognitive and mood status, with a significant dose-response association even with moderate consumption. This might have translational implications for the identification of modifiable factors for vascular dementia and geriatric depression.
    • References:
      Antioxidants (Basel). 2020 Apr 23;9(4):. (PMID: 32340112)
      J Epidemiol. 2020 Aug 5;30(8):338-344. (PMID: 31231097)
      J Anal Toxicol. 2003 Oct;27(7):520-2. (PMID: 14607010)
      Aust N Z J Psychiatry. 2016 Mar;50(3):228-42. (PMID: 26339067)
      Int J Psychophysiol. 2011 Dec;82(3):248-53. (PMID: 21945481)
      Ther Adv Neurol Disord. 2019 Sep 25;12:1756286419878317. (PMID: 31598137)
      J Nutr Health Aging. 2015 Mar;19(3):313-28. (PMID: 25732217)
      Front Psychol. 2017 Apr 12;8:557. (PMID: 28446889)
      J Alzheimers Dis. 2010;20 Suppl 1:S187-204. (PMID: 20182026)
      Dis Markers. 2019 Mar 25;2019:3549402. (PMID: 31019583)
      BMC Med. 2016 Nov 3;14(1):161. (PMID: 27806704)
      Int J Epidemiol. 1996 Jun;25(3):513-20. (PMID: 8671551)
      Mol Nutr Food Res. 2016 Jan;60(1):223-34. (PMID: 26518745)
      Expert Rev Neurother. 2011 May;11(5):677-708. (PMID: 21539488)
      J Clin Neurol. 2020 Jan;16(1):158-159. (PMID: 31942774)
      J Psychiatr Res. 1975 Nov;12(3):189-98. (PMID: 1202204)
      Neural Plast. 2020 Aug 18;2020:8078103. (PMID: 32908482)
      Transl Psychiatry. 2019 Aug 5;9(1):188. (PMID: 31383842)
      Psychosom Med. 2010 Feb;72(2):206-14. (PMID: 19995882)
      Gerontology. 2010;56(3):298-302. (PMID: 20051663)
      Nutrients. 2018 Oct 01;10(10):. (PMID: 30275380)
      J Neurol. 2018 Apr;265(4):968-969. (PMID: 29464373)
      J Alzheimers Dis. 2012;32(3):733-40. (PMID: 22886011)
      Am J Epidemiol. 2002 Nov 1;156(9):842-50. (PMID: 12397002)
      Adv Pharmacol. 2019;84:101-119. (PMID: 31229167)
      Pharmacol Rev. 1999 Mar;51(1):83-133. (PMID: 10049999)
      J Alzheimers Dis. 2014;42(1):119-35. (PMID: 24799342)
      Expert Rev Neurother. 2008 Jan;8(1):133-58. (PMID: 18088206)
      Neurology. 2007 Aug 7;69(6):536-45. (PMID: 17679672)
      BMJ. 1989 Apr 22;298(6680):1075-6. (PMID: 2497897)
      Biomolecules. 2020 Sep 09;10(9):. (PMID: 32916935)
      Am J Clin Nutr. 2009 Sep;90(3):640-6. (PMID: 19587088)
      Neural Plast. 2020 Oct 27;2020:8820881. (PMID: 33193753)
      J Alzheimers Dis. 2018;62(3):1417-1441. (PMID: 29562536)
      Int J Mol Sci. 2020 Apr 23;21(8):. (PMID: 32340195)
      J Alzheimers Dis. 2013;35(2):413-21. (PMID: 23422357)
      Eur J Clin Nutr. 1999 Nov;53(11):831-9. (PMID: 10556993)
      Nutrients. 2018 Sep 19;10(9):. (PMID: 30235886)
      AJR Am J Roentgenol. 1987 Aug;149(2):351-6. (PMID: 3496763)
      Arch Intern Med. 2011 Sep 26;171(17):1571-8. (PMID: 21949167)
      Nutrition. 2016 Jun;32(6):628-36. (PMID: 26944757)
      Brain Sci. 2020 Aug 12;10(8):. (PMID: 32806660)
      J Pers Med. 2020 Dec 12;10(4):. (PMID: 33322688)
      J Stroke Cerebrovasc Dis. 2015 Oct;24(10):2196-9. (PMID: 26255558)
      J Alzheimers Dis. 2010;20 Suppl 1:S127-41. (PMID: 20164568)
      J R Soc Med. 1996 Nov;89(11):618-23. (PMID: 9135590)
      Psychosom Med. 2002 Jul-Aug;64(4):595-603. (PMID: 12140349)
      Front Psychiatry. 2018 Jul 16;9:316. (PMID: 30061847)
      Cerebrovasc Dis. 2009;27(4):384-91. (PMID: 19276621)
      J Stroke Cerebrovasc Dis. 2016 Jul;25(7):1678-1682. (PMID: 27067883)
      Eur J Clin Nutr. 2007 Feb;61(2):226-32. (PMID: 16929246)
      Arch Neurol. 1993 Aug;50(8):873-80. (PMID: 8352676)
      Sci Rep. 2020 Jan 16;10(1):421. (PMID: 31949239)
      Nutrients. 2019 Oct 20;11(10):. (PMID: 31635199)
      J Alzheimers Dis. 2012;30 Suppl 2:S31-75. (PMID: 22561330)
      Biomed Res Int. 2013;2013:351680. (PMID: 23984349)
      Pharmacol Biochem Behav. 2003 Jul;75(4):921-7. (PMID: 12957237)
      Front Physiol. 2020 Sep 18;11:1109. (PMID: 33071804)
      J Neurol Neurosurg Psychiatry. 1960 Feb;23:56-62. (PMID: 14399272)
      J Am Geriatr Soc. 1983 Dec;31(12):721-7. (PMID: 6418786)
      J Alzheimers Dis. 2015;47(4):889-99. (PMID: 26401769)
      Prev Med. 2004 Jan;38(1):114-9. (PMID: 14672648)
      Int J Mol Sci. 2018 Jul 31;19(8):. (PMID: 30065211)
      Adv Nutr. 2013 Jan 01;4(1):115-22. (PMID: 23319129)
      PLoS One. 2017 May 10;12(5):e0177560. (PMID: 28489931)
      BMC Med. 2017 May 24;15(1):107. (PMID: 28539119)
      Phys Sportsmed. 2020 May;48(2):151-160. (PMID: 31646922)
      J Intern Med. 1991 Jun;229(6):501-4. (PMID: 2045756)
      PLoS One. 2014 Apr 17;9(4):e94715. (PMID: 24743309)
      Mol Psychiatry. 2013 Sep;18(9):963-74. (PMID: 23439482)
      J Alzheimers Dis. 2010;20 Suppl 1:S175-85. (PMID: 20182036)
      Annu Rev Nutr. 2017 Aug 21;37:131-156. (PMID: 28826374)
      J Alzheimers Dis. 2020;78(4):1519-1546. (PMID: 33185612)
      Neuroepidemiology. 2015;44(1):51-63. (PMID: 25721193)
      Complement Ther Med. 2018 Jun;38:74-78. (PMID: 29857884)
      Neuroscience. 2012 Jan 27;202:384-95. (PMID: 22155266)
      Neural Plast. 2018 Apr 23;2018:3273246. (PMID: 29849555)
      Clin Nutr. 2017 Jun;36(3):730-736. (PMID: 27288328)
      Nutrients. 2020 May 12;12(5):. (PMID: 32408706)
      PLoS One. 2019 Apr 24;14(4):e0216162. (PMID: 31017968)
      Curr Neuropharmacol. 2005 Oct;3(4):309-16. (PMID: 18369398)
      J Int Med Res. 2020 Feb;48(2):300060519854626. (PMID: 31537137)
      J Clin Med. 2021 Jan 13;10(2):. (PMID: 33451164)
      J Alzheimers Dis. 2011;27(3):553-66. (PMID: 21841254)
      PLoS One. 2015 May 06;10(5):e0126550. (PMID: 25946046)
      BMC Psychiatry. 2013 Nov 09;13:300. (PMID: 24206945)
      J Alzheimers Dis. 2011;23(4):607-15. (PMID: 21157028)
      Alzheimers Dement. 2012 Sep;8(5):445-52. (PMID: 22959699)
      Psychopharmacology (Berl). 1993;110(1-2):45-52. (PMID: 7870897)
      Free Radic Biol Med. 2010 Oct 15;49(7):1212-20. (PMID: 20638472)
    • Contributed Indexing:
      Keywords: caffeine; cerebrovascular disease; coffee consumption; dose-response association; executive dysfunction; geriatric depression
    • Accession Number:
      0 (Coffee)
    • Publication Date:
      Date Created: 20210210 Date Completed: 20210506 Latest Revision: 20210506
    • Publication Date:
      20240104
    • Accession Number:
      PMC7916014
    • Accession Number:
      10.3390/nu13020536
    • Accession Number:
      33562065