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Morbidity and mortality after liver surgery for colorectal liver metastases: a cohort study in a high-volume fast-track programme.

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  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968567 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2482 (Electronic) Linking ISSN: 14712482 NLM ISO Abbreviation: BMC Surg Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, [2001-
    • Subject Terms:
      Colorectal Neoplasms*/surgery ; Liver Neoplasms*/surgery; Cohort Studies ; Humans ; Length of Stay ; Morbidity ; Postoperative Complications/epidemiology
    • Abstract:
      Background: For colorectal liver metastases, surgery is a high-risk procedure due to perioperative morbidity. The objective was to assess severity of complications after fast-track liver surgery for colorectal liver metastases and their impact on morbidity and mortality.
      Methods: All patients were treated according to the same fast-track programme. Complications were graded according to the Clavien-Dindo classification for patients undergoing surgery from 2013 to 2015. Correlation between complications and length of stay was analysed by multivariate linear regression.
      Results: 564 patient cases were included of which three patients died within 3 months (0.53%, 95% CI: 0.17-1.64%). Complications were common with Grade ≤ 2 in 167 patients (30%) and ≥ Grade 3a in 93 (16%). Patients without complications had a mean length of stay of 4.1 days, which increased with complications: 1.4 days (95% CI: 1.3-1.5) for Grade 2, 1.7 days (1.5-2.0) for Grade 3a, 2.3 days (1.7-3.0) for Grade 3b, 2.6 days (1.6-4.2) for Grade 4a, and 2.9 days (2.8-3.1) for Grade 4b. Following were associated with increased length of stay: complication severity grade, liver insufficiency, ascites, biliary, cardiopulmonary, and infectious complications.
      Conclusions: Complications after liver surgery for colorectal liver metastases, in a fast track setting, were associated with low mortality, and even severe complications only prolonged length of stay to a minor degree.
      (© 2021. The Author(s).)
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    • Contributed Indexing:
      Keywords: Colorectal liver metastases; Lenght of stay; Morbidity after surgery; Oncological surgery; Surgical complications
    • Publication Date:
      Date Created: 20210715 Date Completed: 20210716 Latest Revision: 20210718
    • Publication Date:
      20240105
    • Accession Number:
      PMC8278677
    • Accession Number:
      10.1186/s12893-021-01301-4
    • Accession Number:
      34261457