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Enzootic Trypanosoma cruzi infection by Rhodnius prolixus shows transmission to humans and dogs in Vichada, Colombia.

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  • Additional Information
    • Source:
      Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Lausanne : Frontiers Media SA
    • Subject Terms:
      Rhodnius* ; Chagas Disease*/epidemiology ; Chagas Disease*/veterinary ; Trypanosoma cruzi*/genetics; Child ; Humans ; Dogs ; Animals ; Aged ; Seroepidemiologic Studies ; Colombia/epidemiology ; Insect Vectors ; Mammals
    • Abstract:
      Background: Rhodnius prolixus is considered the most relevant Trypanosoma cruzi vector in Colombia and Venezuela due it is responsible for domestic transmission in both countries. However, a wild population of this species is distributed in the eastern plains of the Orinoco region and Amazonia jungle, where its epidemiological importance has not been sufficiently elucidated. This study aimed to assess epidemiological parameters of T. cruzi transmission in the Department of Vichada, Colombia.
      Methods: We determined the characteristics of T. cruzi transmission using entomological studies in domestic and sylvatic ecotopes. We analyzed the T. cruzi infection in triatomine insects, identified blood meal sources, and conducted a serological determination of T. cruzi infection in scholar-aged children, domestic dogs, and wild hosts.
      Results: Fifty-four triatomine bugs, 40 T. maculata and 14 R. prolixus were collected in peridomestic and sylvatic ecotopes. Infected R. prolixus was observed in La Primavera, Santa Rosalia, and Cumaribo municipalities. All the T. maculata bugs were not infected. Serological analysis indicated that two of 3,425 children were T. cruzi positive. The seroprevalence in domestic dogs was 10,5% (49/465). Moreover, 22 synanthropic mammals were sampled, being Didelphis marsupialis the most common. TcI genotype was detected in seropositive dogs, R. prolixus , and D. marsupialis.
      Conclusion: The present work describes extra domestic R. prolixus and D. marsupialis in a sylvatic T. cruzi transmission cycle with transmission to humans and domestic dogs in Colombia's Vichada Department.
      Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
      (Copyright © 2022 Cantillo-Barraza, Solis, Zamora, Herazo, Osorio, Garcés, Xavier, Mejía-Jaramillo and Triana-Chávez.)
    • References:
      Biomedica. 2007 Jan;27 Suppl 1:143-62. (PMID: 18154255)
      J Vector Borne Dis. 2010 Jun;47(2):76-84. (PMID: 20539044)
      PLoS One. 2019 Jan 7;14(1):e0210156. (PMID: 30615644)
      Acta Trop. 2020 Sep;209:105550. (PMID: 32473116)
      Mol Ecol. 2012 Sep;21(17):4216-26. (PMID: 22774844)
      Wkly Epidemiol Rec. 2015 Feb 6;90(6):33-43. (PMID: 25671846)
      Mem Inst Oswaldo Cruz. 2007 Oct 30;102 Suppl 1:29-38. (PMID: 17891273)
      Parasit Vectors. 2019 Jun 20;12(1):308. (PMID: 31221188)
      Biomedica. 2017 Jun 01;37(2):218-232. (PMID: 28527286)
      Parasit Vectors. 2016 Dec 1;9(1):620. (PMID: 27903288)
      J Clin Microbiol. 1989 Jul;27(7):1477-82. (PMID: 2504769)
      Prev Vet Med. 2020 Nov;184:105159. (PMID: 33038611)
      Acta Trop. 2007 Feb;101(2):169-77. (PMID: 17306204)
      Mol Biochem Parasitol. 1996 Dec 20;83(2):141-52. (PMID: 9027747)
      Parasit Vectors. 2015 Sep 22;8:482. (PMID: 26394766)
      J Vector Ecol. 2016 Jun;41(1):72-9. (PMID: 27232127)
      Zoonoses Public Health. 2014 Nov;61(7):477-9. (PMID: 25285940)
      Parasit Vectors. 2021 Oct 9;14(1):519. (PMID: 34625109)
      Parasite Epidemiol Control. 2020 Aug 05;11:e00171. (PMID: 32875129)
      Rev Inst Med Trop Sao Paulo. 2005 May-Jun;47(3):131-7. (PMID: 16021285)
      Front Public Health. 2014 Sep 30;2:170. (PMID: 25325053)
      Int J Parasitol. 2010 Dec;40(14):1599-607. (PMID: 20670628)
      Prev Vet Med. 2017 Jun 1;141:1-6. (PMID: 28532988)
      Infect Genet Evol. 2013 Dec;20:148-54. (PMID: 24012949)
      Acta Trop. 2020 Oct;210:105504. (PMID: 32526167)
      Am J Trop Med Hyg. 2006 May;74(5):762-5. (PMID: 16687677)
      Sci Data. 2018 Apr 24;5:180071. (PMID: 29688221)
      Vector Borne Zoonotic Dis. 2019 Feb;19(2):81-89. (PMID: 30156473)
      PLoS Negl Trop Dis. 2012;6(2):e1530. (PMID: 22389739)
      PLoS Negl Trop Dis. 2010 Dec 14;4(12):e915. (PMID: 21179502)
      Infect Genet Evol. 2012 Mar;12(2):240-53. (PMID: 22226704)
      Vet Parasitol. 2013 Sep 1;196(1-2):216-9. (PMID: 23351975)
      Parasit Vectors. 2014 Aug 20;7:381. (PMID: 25141852)
      Mem Inst Oswaldo Cruz. 2009 Jul;104 Suppl 1:71-5. (PMID: 19753461)
      Mem Inst Oswaldo Cruz. 2015 May;110(3):283-8. (PMID: 25830543)
    • Contributed Indexing:
      Keywords: Chagas disease; Colombia; Didelphis marsupialis; Rhodnius prolixus; Triatoma maculata; Trypanosoma cruzi
    • Publication Date:
      Date Created: 20221104 Date Completed: 20221107 Latest Revision: 20221222
    • Publication Date:
      20240105
    • Accession Number:
      PMC9623245
    • Accession Number:
      10.3389/fcimb.2022.999082
    • Accession Number:
      36329821