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The effect of using nitroderm TTS in ERCP on precut, selective cannulation, and bleeding.

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  • Author(s): Calta AF;Calta AF; Duran A; Duran A
  • Source:
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES [Ulus Travma Acil Cerrahi Derg] 2023 Mar; Vol. 29 (3), pp. 344-349.
  • Publication Type:
    Journal Article
  • Language:
    English
  • Additional Information
    • Transliterated Title:
      ERCP işleminde nitroderm TTS kullanımının precut, selektif kanülasyon ve kanama üzerine etkisi.
    • Source:
      Publisher: KARE Yayıncılık Country of Publication: Turkey NLM ID: 101274231 Publication Model: Print Cited Medium: Internet ISSN: 1307-7945 (Electronic) Linking ISSN: 1306696X NLM ISO Abbreviation: Ulus Travma Acil Cerrahi Derg Subsets: MEDLINE
    • Publication Information:
      Publication: Kadıköy, İstanbul : KARE Yayıncılık
      Original Publication: [Istanbul] : Ulusal Travma ve Acil Cerrahi Derneği, [2003]-
    • Subject Terms:
      Cholangiopancreatography, Endoscopic Retrograde*/adverse effects ; Pancreatitis*; Humans ; Nitroglycerin ; Retrospective Studies ; Hemorrhage/etiology ; Catheterization/adverse effects
    • Abstract:
      Background: The aim of the study was to investigate the use of prophylactic nitroglycerin patch in patients who applied to our clinic with occlusion icter and underwent endoscopic retrograde cholangiopancreatography (ERCP) for complications such as pancreatitis, bleeding, perforation that may occur during and after the procedure, duration of the procedure, length of hospitalization, precut and selective cannulation rates, and mortality.
      Methods: Patients were searched retrospectively using the hospital database. Patients under the age of 18, patients with poor general condition and patients treated under emergency conditions were excluded from the study. The effects of the drug on morbidity, mortality, duration of procedure, length of hospital stay, and cannulation techniques were investigated in patient groups with and without nitroglycerin patch.
      Results: It was observed that using nitroglycerin decreased the precut probability by 2.28 times (p<0.001), and decreased periop-erative bleeding by 3.4 times (p<0.001). 75.1% selective cannulation was observed in the group not administered nitroglycerin, this rate was determined as 87.3% in the group administered nitroderm(p<0.001). In the regression model, it was observed that the presence of nitroderm increased the probability of selective cannulation 2.21 times (p<0.001). The effects of nitroglycerin use on mortality, patient's history of malignancy, presence of stones and mud, gender, age, post-operative pancreatitis, and perioperative bleeding variables were evaluated by regression analysis, and age increased mortality by 1.09 (p=0.023).
      Conclusion: It has been shown that the use of prophylactic nitroglycerin patch in ERCP procedure increases the prophylactic selective cannulation rate, shortens the precut rate, pre-operative bleeding, hospital stay, and procedure time.
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    • Accession Number:
      G59M7S0WS3 (Nitroglycerin)
    • Publication Date:
      Date Created: 20230307 Date Completed: 20230308 Latest Revision: 20230603
    • Publication Date:
      20240104
    • Accession Number:
      PMC10225847
    • Accession Number:
      10.14744/tjtes.2022.07665
    • Accession Number:
      36880619