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MORTALIDAD Y DESENLACES CLÍNICOS EN PACIENTES CRÍTICAMENTE ENFERMOS CON INFECCIONES POR BACTERIAS PRODUCTORAS DE CARBAPENEMASAS EN UN HOSPITAL DE ALTA COMPLEJIDAD EN BOGOTÁ, COLOMBIA

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  • Additional Information
    • Publication Information:
      Asociación Colombiana de Infectología
    • Publication Date:
      1478
    • Collection:
      Directory of Open Access Journals: DOAJ Articles
    • Abstract:
      Introduction: Microorganisms able to produce carbapenemases are spreading worldwide and have become a concerning global public-health problem. In Colombia, the Gram-negative resistance to carbapenems at intensive care units is currently increasing and its impact on clinical outcomes is not well known. Objectives: To determine the demographic, clinical characteristics and outcomes of critically ill adult patients with infection by carbapenemase producing bacteria in a polyvalent intensive care unit of a highly complex institution. Methods: Single-center retrospective, descriptive observational study including critically ill adult patients infected by carbapenemase-producing bacteria and transferred to a polyvalent intensive care unit from January 1th 2014 to January 1th 2018. Known colonized patients were excluded. Clinical complications, ICU and in-hospital days of stay were evaluated, as ICU and in-hospital mortality. Results: A total of 58 patients were included. Overall mortality was 67.2%, of which 55.17% died during their stay in the intensive care unit and 12.06% in hospitalization. The median stay in the intensive care unit was 18 days (IQR 4-28). The most frequent cause of death was septic shock in 51% and the most common complications were acute renal injury and delirium in 55.2% and 43.1%, respectively. The median stay in the ICU was 18 days (RIQ 4-28). Conclusions: Infections caused by carbapenem-resistant bacteria in critically ill patients are associated with high mortality rates, complications and long stay in ICU.
    • ISSN:
      0123-9392
    • Relation:
      https://www.revistainfectio.org/index.php/infectio/article/view/903; https://doaj.org/toc/0123-9392; https://doaj.org/article/989054b0f9cd401d9062b35d17f1a5b6
    • Accession Number:
      10.22354/in.v25i1.903
    • Accession Number:
      edsbas.78140FA7