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Anticancer mechanisms of β-carbolines.

• Authors : Mishra S; Pharmacy College Saifai, Uttar Pradesh University of Medical Sciences, Etawah, Uttar Pradesh, India.; Gupta A

Subjects: Carbolines*/Carbolines*/Carbolines*/chemistry ; Carbolines*/Carbolines*/Carbolines*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

• Source: Chemical biology & drug design [Chem Biol Drug Des] 2024 Apr; Vol. 103 (4), pp. e14521.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285

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Synthesis of 1,4‐Disubstituted and 1‐Substituted β‐Carbolines via 3‐Substituted 2‐Acylindoles.

• Authors : Thees, Katharina¹ (AUTHOR); Untergehrer, Martin¹ (AUTHOR); Jourjine, Ilya A. P.¹ (AUTHOR)

• Source: European Journal of Organic Chemistry. 5/21/2024, Vol. 27 Issue 19, p1-8. 8p.

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Synthesis of α‐ and β‐Carbolines by a Metalation/Negishi Cross‐Coupling/SNAr Reaction Sequence.

• Authors : Sathiyalingam, Shainthavaan¹ (AUTHOR); Roesner, Stefan¹ (AUTHOR)

• Source: Advanced Synthesis & Catalysis. 5/17/2022, Vol. 364 Issue 10, p1769-1774. 6p.

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The effect of onion and garlic on non-polar heterocyclic aromatic amines (α-, β-, γ- and δ-carbolines) formation in pan-fried meat and gravy.

• Authors : Śnieżek, Ewa¹ (AUTHOR); Szumska, Magdalena¹ (AUTHOR); Nowak, Agnieszka¹ (AUTHOR)

Subjects: *Garlic; *Aromatic amines; *Solid phase extraction

• Source: Food Additives & Contaminants. Part A: Chemistry, Analysis, Control, Exposure & Risk Assessment. Jan 2022, Vol. 39 Issue 1, p35-51. 17p. 1 Color Photograph, 1 Diagram, 3 Charts, 3 Graphs.

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Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer.

• Authors : Ling J; School of Basic Medical Sciences, Ningxia Medical University, Ningxia, 750004, Yinchuan, China.; The Laboratory Medicine Department of Shanxi Provincial People Hospital, Taiyuan, 030001, China.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism

• Source: Cell communication and signaling : CCS [Cell Commun Signal] 2025 Jul 08; Vol. 23 (1), pp. 326. Date of Electronic Publication: 2025 Jul 08.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Antitumor Activity of Tetrahydro-β-carboline Derivatives via Inhibition of Kinesin Spindle Protein: Validation by Molecular Docking, Molecular Dynamics, and In Vitro Assays.

• Authors : Guo S; College of Science, Yunnan Agricultural University, Kunming 650201, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China.

Subjects: Carbolines*/Carbolines*/Carbolines*/pharmacology ; Carbolines*/Carbolines*/Carbolines*/chemistry ; Kinesins*/Kinesins*/Kinesins*/antagonists & inhibitors

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jun 04; Vol. 26 (11). Date of Electronic Publication: 2025 Jun 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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1-Phenyl-β-carboline-3-carboxamide-1,2,3-triazole-N-phenylacetamide hybrids as new α-glucosidase inhibitors.

• Authors : Safaie E; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.; Sayahi MH

Subjects: Glycoside Hydrolase Inhibitors*/Glycoside Hydrolase Inhibitors*/Glycoside Hydrolase Inhibitors*/chemistry ; Glycoside Hydrolase Inhibitors*/Glycoside Hydrolase Inhibitors*/Glycoside Hydrolase Inhibitors*/pharmacology ; Glycoside Hydrolase Inhibitors*/Glycoside Hydrolase Inhibitors*/Glycoside Hydrolase Inhibitors*/chemical synthesis

• Source: Scientific reports [Sci Rep] 2025 May 20; Vol. 15 (1), pp. 17418. Date of Electronic Publication: 2025 May 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Consecutive Four-Component Coupling-Addition Aza-Anellation Pictet – Spengler Synthesis of Tetrahydro- β -Carbolines: An Optimized Michael Addition and Computational Study on the Aza-Anellation Step.

• Authors : Ries, Kai¹ ; Aouane, Françoise A.¹; Müller, Thomas J. J.¹

• Source: Organics. Sep2023, Vol. 4 Issue 3, p313-332. 20p.

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Synthesis and diverse biological activities of substituted indole β-carbolines: a review

• Authors : Siti Zafirah Zulkifli; Noor Hidayah Pungot; Aimi Suhaily Saaidin

Subjects: Antimalarials; Indoles; Molecular Structure

• Source: Natural Product Research. 38:3793-3806

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Novel access to α-carbolines with biological applications

• Authors : Provot, Olivier;

Subjects: Synthesis; Biological Products; Carboline

• Source: European Journal of Medicinal ChemistryEuropean Journal of Medicinal Chemistry, 2024, 276, pp.116700. ⟨10.1016/j.ejmech.2024.116700⟩

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