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A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens

• Authors : Mattson, Nicole M; Chan, Anthony KN; Miyashita, Kazuya

Subjects: Biochemistry and Cell Biology; Biological Sciences; Cancer

• Source: Nature Structural & Molecular Biology. 31(3)

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The selection landscape and genetic legacy of ancient Eurasians

• Authors : Irving-Pease, Evan K; Refoyo-Martínez, Alba; Barrie, William

Subjects: Biological Sciences; Genetics; History

• Source: Nature. 625(7994)

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Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

• Authors : Barrie, William; Yang, Yaoling; Irving-Pease, Evan K

Subjects: Biological Sciences; Genetics; History

• Source: Nature. 625(7994)

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Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development

• Authors : Schiedel, Matthias; McArdle, Darius JB; Padalino, Gilda

Subjects: Medicinal and Biomolecular Chemistry; Organic Chemistry; Chemical Sciences

• Source: Journal of Medicinal Chemistry. 66(23)

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Molecular and Cellular Effects of Chemical Chaperone—TUDCA on ER-Stressed NHAC-kn Human Articular Chondrocytes Cultured in Normoxic and Hypoxic Conditions

• Authors : Rafał Krętowski; Marzanna Cechowska-Pasko; Magdalena Kusaczuk

Subjects: Cartilage, Articular; 0301 basic medicine; Interleukin-1beta

• Source: Molecules, Vol 26, Iss 878, p 878 (2021)MoleculesVolume 26Issue 4

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Standards recommendations for the Earth BioGenome Project

• Authors : Lawniczak, Mara KN; Durbin, Richard; Flicek, Paul

Subjects: Human Genome; Genetics; Animals

• Source: Proceedings of the National Academy of Sciences of the United States of America. 119(4)

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Why sequence all eukaryotes?

• Authors : Blaxter, Mark; Archibald, John M; Childers, Anna K

Subjects: Biotechnology; Animals; Base Sequence

• Source: Proceedings of the National Academy of Sciences of the United States of America. 119(4)

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Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group

• Authors : Lacas, Benjamin; Carmel, Alexandra; Landais, Cécile

Subjects: Cancer; Clinical Trials and Supportive Activities; Rare Diseases

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Conformational dynamics of androgen receptors bound to agonists and antagonists

• Authors : Gim, Hyo Jin; Park, Jiyong; Jung, Michael E

Subjects: Biochemistry and Cell Biology; Chemical Sciences; Biological Sciences

• Source: Scientific Reports. 11(1)

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Measurements of adiposity as prognostic biomarkers for survival with anti-angiogenic treatment in epithelial ovarian cancer: An NRG Oncology/Gynecologic Oncology Group ancillary data analysis of GOG 218

• Authors : Wade, KN Slaughter; Brady, MF; Thai, T

Subjects: Clinical Trials and Supportive Activities; Cancer; Clinical Research

• Source: Gynecologic Oncology. 155(1)

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