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Academic Journal

A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long-term inflammatory exposure: A Canadian Longitudinal Study on Aging analysis.

  • Authors : Verschoor CP; Health Sciences North Research Institute, Sudbury, Ontario, Canada.; Northern Ontario School of Medicine, Sudbury, Ontario, Canada.

Subjects: C-Reactive Protein*/C-Reactive Protein*/C-Reactive Protein*/metabolism ; DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics; Humans

  • Source: Aging cell [Aging Cell] 2023 Jul; Vol. 22 (7), pp. e13863. Date of Electronic Publication: 2023 May 04.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Region-based epigenetic clock design improves RRBS-based age prediction.

  • Authors : Simpson DJ; MRC Human Genetics Unit, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Zhao Q

Subjects: DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics ; Epigenomics*; Mice

  • Source: Aging cell [Aging Cell] 2023 Aug; Vol. 22 (8), pp. e13866. Date of Electronic Publication: 2023 May 11.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.

  • Authors : Tharakan R; Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.

Subjects: Aging*/Aging*/Aging*/genetics ; DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics; Humans

  • Source: Aging cell [Aging Cell] 2023 Jul; Vol. 22 (7), pp. e13847. Date of Electronic Publication: 2023 Jun 12.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

A decrease in NR2B expression mediated by DNA hypermethylation induces perioperative neurocognitive disorder in aged mice.

  • Authors : Xu F; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.; Cong P

Subjects: Cognition Disorders*/Cognition Disorders*/Cognition Disorders*/metabolism ; DNA Methylation* ; Receptors, N-Methyl-D-Aspartate*/Receptors, N-Methyl-D-Aspartate*/Receptors, N-Methyl-D-Aspartate*/genetics

  • Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 May; Vol. 29 (5), pp. 1229-1242. Date of Electronic Publication: 2023 Jan 24.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print-Electronic Cited

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Academic Journal

Deciphering the role of immune cell composition in epigenetic age acceleration: Insights from cell-type deconvolution applied to human blood epigenetic clocks.

  • Authors : Zhang Z; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.

Subjects: Acceleration* ; Arthritis, Rheumatoid*; Humans

  • Source: Aging cell [Aging Cell] 2024 Mar; Vol. 23 (3), pp. e14071. Date of Electronic Publication: 2023 Dec 25.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV.

  • Authors : Corley MJ; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York City, New York, USA.; Pang APS

Subjects: Metformin*/Metformin*/Metformin*/pharmacology ; Metformin*/Metformin*/Metformin*/therapeutic use ; HIV Infections*/HIV Infections*/HIV Infections*/drug therapy

  • Source: Aging cell [Aging Cell] 2024 Jan; Vol. 23 (1), pp. e13926. Date of Electronic Publication: 2023 Sep 07.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Skeletal muscle DNA methylation: Effects of exercise and HIV.

  • Authors : Jankowski CM; College of Nursing, University of Colorado Anschutz Medical Campus, Colorado, Aurora, USA.; Konigsberg IR

Subjects: Frailty*/Frailty*/Frailty*/genetics ; HIV Infections*/HIV Infections*/HIV Infections*/genetics; Humans

  • Source: Aging cell [Aging Cell] 2024 Jan; Vol. 23 (1), pp. e14025. Date of Electronic Publication: 2023 Nov 03.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Role of DNA methylation in cancer development and its clinical applications.

  • Source: Clinical & Translational Discovery. Feb2024, Vol. 4 Issue 1, p1-6. 6p.

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Academic Journal

Polygenic risk for schizophrenia, social dispositions, and pace of epigenetic aging: Results from the Young Finns Study.

  • Authors : Saarinen A; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Helsinki University Central Hospital, Adolescent Psychiatry Outpatient Clinic, Helsinki, Finland.

Subjects: Schizophrenia*/Schizophrenia*/Schizophrenia*/genetics; Humans ; Genome-Wide Association Study

  • Source: Aging cell [Aging Cell] 2024 Mar; Vol. 23 (3), pp. e14052. Date of Electronic Publication: 2023 Nov 29.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

DNA repair-deficient premature aging models display accelerated epigenetic age.

  • Authors : Perez K; Department of Biomedical Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.; EPITERNA SA, Epalinges, Switzerland.

Subjects: Aging, Premature*/Aging, Premature*/Aging, Premature*/genetics; Humans ; Mice

  • Source: Aging cell [Aging Cell] 2024 Feb; Vol. 23 (2), pp. e14058. Date of Electronic Publication: 2023 Dec 22.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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