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Telomeres.

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  • Author(s): Manning, Elizabeth A., PhD; Singer, Sanford S.;Manning, Elizabeth A., PhD; Singer, Sanford S.
  • Source:
    Salem Press Encyclopedia of Health, 2026. 3p.
  • Subject Terms:
    Eukaryotic cell genetics; Telomerase; Telomeres
  • Additional Information
    • Abstract:
      SIGNIFICANCE: Telomeres, the ends of the arms of chromosomes of eukaryotes, become shorter as organisms age. They are thought to act biologically to slow chromosome shortening, which can lead to cell death caused by the loss of genes and may be related to aging and diseases such as cancer. Telomeric DNA may also be involved in chromosome movement and localization in the nucleus, as well as transcriptional regulation of genes near the telomeres.