Abstract: International audience ; The growing demand for organ transplantation and the shortage of available organs has led to the use of extended criteria donors and perfusion machines to expand the donor pool. However, current clinical practice lacks effective methods for real-time graft monitoring during perfusion. Graft monitoring on perfusion machines represents a promising approach for continuous assessment of their functional status . During the reperfusion phase, it becomes possible to monitor the graft's condition in real-time through the study of respiratory chain metabolites. This respiratory chain is particularly affected during ischemia and reperfusion phases, making its monitoring essential for optimizing preservation conditions and predicting graft viability prior to transplantation.
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