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The Intratumoral Distribution of Radiolabeled 177Lu-BR96 Monoclonal Antibodies Changes in Relation to Tumor Histology over Time in a Syngeneic Rat Colon Carcinoma Model.

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  • Additional Information
    • Publication Information:
      Society of Nuclear Medicine Inc.
    • Publication Date:
      2013
    • Collection:
      Lund University Publications (LUP)
    • Abstract:
      The therapeutic effect of radioimmunotherapy depends on the distribution of the absorbed dose in relation to viable cancer cells within the tumor, which in turn is a function of the activity distribution. The aim of this study was to investigate the distribution of (177)Lu-DOTA-BR96 monoclonal antibodies targeting the Lewis Y antigen over 7 d using a syngeneic rat model of colon carcinoma.
    • File Description:
      application/pdf
    • Relation:
      https://lup.lub.lu.se/record/3912939; http://dx.doi.org/10.2967/jnumed.112.117028; https://portal.research.lu.se/files/2390625/4144958.pdf; wos:000322692400054; pmid:23804328; scopus:84876839931
    • Accession Number:
      10.2967/jnumed.112.117028
    • Online Access:
      https://lup.lub.lu.se/record/3912939
      https://doi.org/10.2967/jnumed.112.117028
      https://portal.research.lu.se/files/2390625/4144958.pdf
    • Rights:
      info:eu-repo/semantics/openAccess
    • Accession Number:
      edsbas.CDF06BE