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Synthetic biology: scientific and social aspects ; Biología sintética: aspectos científicos y sociales

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  • Additional Information
    • Publication Information:
      Consejo Superior de Investigaciones Científicas
    • Publication Date:
      2014
    • Collection:
      Arbor (E-Journal)
    • Abstract:
      On 20 May 2010, Craig Venter announced that he had created the first self-replicating synthetic genome capable of controlling the metabolic behaviour of host cells. The reaction to Venter’s announcement was surprise and amazement, but raised a range of alarms from enlightened enthusiasm to exclamations of uncertainty: What did this announcement mean? Biology had entered the digital age. Claims about potential risks and benefits invaded the scientific world. Were we approaching the “creation of life” by design? What is the difference between living and non-living matter? Was the organism generated by chemical synthesis the same as that which had been designed? The challenge was to find the conditions in which the genomes and the enucleated hosts could function in unison. Do we have enough knowledge to design interactions between biological units capable of generating new organisms? Scientists have used DNA to modify cells and organisms. In fact, a large industry has grown up based on recombinant DNA technology. Could synthetic biology play a clinical role?. ; El 20 de Mayo de 2010 Craig Venter anunció que se había creado el primer genoma sintético auto-replicativo capaz de controlar el comportamiento metabólico de las células huésped. La reacción al anuncio de Venter fue de sorpresa y asombro, pero levantó toda una gama de alarmas desde entusiasmos alumbrados a exclamaciones de incertidumbre: ¿Qué quería decir este anuncio? La biología entraba en la era digital y afirmaciones sobre potenciales riesgos y beneficios invadieron el mundo científico. ¿Estamos acercándonos a la “creación de vida” mediante diseño? ¿Se podría crear materia viva a partir de materia no viva? ¿Cuál es la diferencia entre materia viva y no-viva? ¿El organismo que se había generado por síntesis química era el que se había diseñado? El reto estaba en saber diseñar las condiciones para que los genomas y los huéspedes funcionaran al unísono. El reto es, por tanto, científico, pero lo es igualmente técnico. ¿Tenemos los conocimientos suficientes ...
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    • Relation:
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    • Accession Number:
      10.3989/arbor.2014.768n4002
    • Online Access:
      https://arbor.revistas.csic.es/index.php/arbor/article/view/1950
      https://doi.org/10.3989/arbor.2014.768n4002
    • Rights:
      Derechos de autor 2014 Consejo Superior de Investigaciones Científicas (CSIC) ; https://creativecommons.org/licenses/by/4.0
    • Accession Number:
      edsbas.F10898C3