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Academic Journal

An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma

Subjects: Humans; immune checkpoint inhibitors; Immune Checkpoint Inhibitors - therapeutic use - pharmacology

  • Source: Baxter, M A, Spender, L C, Cairns, D, Walsh, S, Oparka, R, Porter, R J, Bray, S, Skinner, G, King, S, Turbitt, J, Collinson, D, Miedzybrodzka, Z H, Jellema, G, Logan, G, Kennedy, R D, Turkington, R C,

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Academic Journal

An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma

Subjects: Humans; immune checkpoint inhibitors; Immune Checkpoint Inhibitors - therapeutic use - pharmacology

  • Source: Baxter, M A, Spender, L C, Cairns, D, Walsh, S, Oparka, R, Porter, R J, Bray, S, Skinner, G, King, S, Turbitt, J, Collinson, D, Miedzybrodzka, Z H, Jellema, G, Logan, G, Kennedy, R D, Turkington, R C,

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Academic Journal

Monte Carlo damage models of different complexity levels predict similar trends in radiation induced DNA damage

Subjects: Monte Carlo; radiation biology; DNA damage

  • Source: Thompson, S J, Prise, K M & McMahon, S J 2024, 'Monte Carlo damage models of different complexity levels predict similar trends in radiation induced

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Academic Journal

Monte Carlo damage models of different complexity levels predict similar trends in radiation induced DNA damage

Subjects: Monte Carlo; radiation biology; DNA damage

  • Source: Thompson, S J, Prise, K M & McMahon, S J 2024, 'Monte Carlo damage models of different complexity levels predict similar trends in radiation induced

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Academic Journal

Integrated multimodal analyses of DNA damage response and immune markers as predictors of response in metastatic triple-negative breast cancer in the TNT trial (NCT00532727)

Subjects: Humans; Carboplatin; BRCA1 Protein/genetics

  • Source: Tovey, H, Sipos, O, Parker, J S, Hoadley, K A, Quist, J, Kernaghan, S, Kilburn, L, Salgado, R, Loi, S, Kennedy, R D, Roxanis, I, Gazinska, P, Pinder, S E, Bliss, J, Perou, C M, Haider, S, Grigoriadis,

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Academic Journal

Integrated multimodal analyses of DNA damage response and immune markers as predictors of response in metastatic triple-negative breast cancer in the TNT trial (NCT00532727)

Subjects: Humans; Carboplatin; BRCA1 Protein/genetics

  • Source: Tovey, H, Sipos, O, Parker, J S, Hoadley, K A, Quist, J, Kernaghan, S, Kilburn, L, Salgado, R, Loi, S, Kennedy, R D, Roxanis, I, Gazinska, P, Pinder, S E, Bliss, J, Perou, C M, Haider, S, Grigoriadis,

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Academic Journal

A DNA-damage immune response assay combined with PET biomarkers predicts response to neo-adjuvant chemotherapy and survival in oesophageal adenocarcinoma

Subjects: Adenocarcinoma/diagnostic imaging; Adult; Aged

  • Source: Foley, K G, Lavery, A, Napier, E, Campbell, D, Eatock, M M, Kennedy, R D, Bradley, K M & Turkington, R C 2021, 'A DNA-damage immune

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Academic Journal

A DNA-damage immune response assay combined with PET biomarkers predicts response to neo-adjuvant chemotherapy and survival in oesophageal adenocarcinoma

Subjects: Adenocarcinoma/diagnostic imaging; Adult; Aged

  • Source: Foley, K G, Lavery, A, Napier, E, Campbell, D, Eatock, M M, Kennedy, R D, Bradley, K M & Turkington, R C 2021, 'A DNA-damage immune

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Academic Journal

Oxygen enhancement ratios of cancer cells after exposure to intensity modulated x-ray fields: DNA damage and cell survival

Subjects: Cell survival; DNA damage; Intensity modulated radiation fields

  • Source: Matsuya, Y, McMahon, S J, Butterworth, K T, Naijo, S, Nara, I, Yachi, Y, Saga, R, Ishikawa, M, Sato, T, Date, H & Prise, K M 2021, 'Oxygen enhancement ratios of cancer cells after exposure to

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