Search Results

Phase 2a, Randomized Trial of Mitiperstat Versus Placebo in Patients with COPD at High Risk of Exacerbation (CRESCENDO)

• Authors : Hughes, Rod; Brailsford, Wayne; Ferreira, João

Subjects: airway neutrophilia; exacerbations of COPD; inflammation

• Source: Hughes, R, Brailsford, W, Ferreira, J, Chalmers, J D, Belvisi, M G, Kocks, J W H, Masters, P, Thomson, P, Łyżwa, D, Rosengren, S, Cooper, J D, Russell, R E K & Saralaya, D 2025, 'Phase 2a,

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Assessment of the role of small airway dysfunction in relation to exacerbation risk in patients with well controlled asthma (ATLANTIS):an observational study

• Authors : Galant, Stanley P; Kuks, Pauline J M; Kole, Tessa M

• Source: Galant, S P, Kuks, P J M, Kole, T M, Kraft, M, Siddiqui, S, Fabbri, L M, Beghé, B, Rabe, K F, Papi, A, Brightling, C E, Singh, D, Kocks, J W H, Franzini, L, Vonk, J M, Kerstjens, H A M, Heijink, I H,

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The disruptive effects of COPD exacerbation-associated factors on epithelial repair responses

• Authors : Kortekaas, Rosa K; Geillinger-Kästle, Kerstin E; Fuentes-Mateos, Rocío

Subjects: Animals; Pulmonary Disease; Chronic Obstructive/metabolism

• Source: Kortekaas, R K, Geillinger-Kästle, K E, Fuentes-Mateos, R, van Orsoy, R, Al-Alyan, N, Burgess, J K & Gosens, R 2024, 'The disruptive effects of COPD

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Tumstatin fragment selectively inhibits neutrophil infiltration in experimental asthma exacerbation

• Authors : Nissen, Gyde; Hollaender, Henrike; Tang, Francesca S. M.

Subjects: asthma; exacerbation; innate immunity

• Source: Nissen, G, Hollaender, H, Tang, F S M, Wegmann, M, Lunding, L, Vock, C, Bachmann, A, Lemmel, S, Bartels, R, Oliver, B G, Burgess, J K, Becker, T, Kopp, M V & Weckmann, M 2018, 'Tumstatin fragment

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The effect of COPD severity and study duration on exacerbation outcome in randomized controlled trials

• Authors : Eriksson, Goran; Calverley, Peter M.; Jenkins, Christine R.

Subjects: healthy survivor effect; exacerbation outcomes; early differential dropout

• Source: Eriksson, G, Calverley, P M, Jenkins, C R, Anzueto, A R, Make, B J, Lindberg, M, Fageras, M & Postma, D S 2017, 'The effect of COPD severity and study duration on

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Serological neo-epitope extracellular matrix related markers reflecting collagen or elastin degradation are elevated in a mouse model of allergic asthma exacerbation

• Authors : Weckmann, M.; Rønnow, S.; Bülow-Sand, J.M.

Subjects: collagen type 1; elastin; endogenous compound

• Source: Weckmann, M, Rønnow, S, Bülow-Sand, J M, Wegmann, M, Lunding, L, Burgess, J, Bahmer, T, Leeming, D J & Kopp, M V 2018, 'Serological neo-epitope extracellular matrix related markers reflecting

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Tiotropium improves lung function, exacerbation rate, and asthma control, independent of baseline characteristics including age, degree of airway obstruction, and allergic status

• Authors : Kerstjens, Huib A. M.; Moroni-Zentgraf, Petra; Tashkin, Donald P.

Subjects: Asthma worsening; FEV1; Respimat (R)

• Source: Kerstjens, H A M, Moroni-Zentgraf, P, Tashkin, D P, Dahl, R, Paggiaro, P, Vandewalker, M, Schmidt, H, Engel, M & Bateman, E D 2016, 'Tiotropium improves lung function,

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Responsivity and Reproducibility of Sputum Inflammatory Biomarkers During COPD Exacerbation and Stable Phases - A Pilot Study

• Authors : Ditz, B; Kistemaker, L E M; van den Berge, M

• Source: Ditz, B, Kistemaker, L E M, van den Berge, M, Vonk, J M, Gosens, R & Kerstjens, H A M 2021, 'Responsivity and Reproducibility of Sputum Inflammatory Biomarkers During COPD

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Relationship between biomarkers and findings on low-dose computed tomography in hospitalised patients with acute exacerbation of COPD

• Authors : Prins, Hendrik J.; Duijkers, Ruud; Kramer, Gerdien

Subjects: COMMUNITY-ACQUIRED PNEUMONIA; C-REACTIVE PROTEIN; QUALITY-OF-LIFE

• Source: Prins, H J, Duijkers, R, Kramer, G, Boerhout, E, Rietema, F J, de Jong, P A, Schoorl, M, van der Werf, T S & Boersma, W G 2022, 'Relationship between biomarkers and findings on low-dose computed

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Risk factors for asthma exacerbation during pregnancy:protocol for a systematic review and meta-analysis

• Authors : Bokern, Marleen P.; Robijn, Annelies L.; Jensen, Megan E.

Subjects: Asthma; Pregnancy; Risk factors

• Source: Bokern, M P, Robijn, A L, Jensen, M E, Barker, D, Baines, K J & Murphy, V E 2022, 'Risk factors for asthma exacerbation during pregnancy : protocol for a systematic

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