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Drug Safety Assessment Based on Target Affinity, Drug Exposure and Plasma Protein Binding: Drug-Induced Cardiotoxicity from a Translational Pharmacology Perspective.

• Authors : Catozzi S; Sips F ...

Subjects: Cardiotoxicity*/Cardiotoxicity*/Cardiotoxicity*/metabolism ; Cardiotoxicity*/Cardiotoxicity*/Cardiotoxicity*/etiology ; Blood Proteins*/Blood Proteins*/Blood Proteins*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2026 May 19; Vol. 27 (10). Date of Electronic Publication: 2026 May 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Label-Free and Immobilization-Free Protein-Binding Assays by Ultraviolet Transient Absorption Microscopy.

• Authors : Shen J; Institute of Medical Photonics, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.; Wang Q

Subjects: Microscopy*/Microscopy*/Microscopy*/methods ; Serum Albumin, Bovine*/Serum Albumin, Bovine*/Serum Albumin, Bovine*/metabolism ; Serum Albumin, Bovine*/Serum Albumin, Bovine*/Serum Albumin, Bovine*/chemistry

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Apr; Vol. 13 (19), pp. e19985. Date of Electronic Publication: 2026 Jan 27.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Evaluation of toxicokinetic interactions mediated by plasma protein binding during amoxapine intoxication.

• Authors : Okamoto A; Department of Toxicology, Showa Medical University Graduate School of Pharmacy.; Showa Medical University Pharmacological Research Center.

Subjects: Amoxapine*/Amoxapine*/Amoxapine*/toxicity ; Amoxapine*/Amoxapine*/Amoxapine*/blood ; Amoxapine*/Amoxapine*/Amoxapine*/pharmacokinetics

• Source: The Journal of toxicological sciences [J Toxicol Sci] 2026; Vol. 51 (1), pp. 31-44.Publisher: Doku Sayō Kenkyūkai Country of Publication: Japan NLM ID: 7805798 Publication Model: Print Cited Medium: Internet ISSN: 1880-3989

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Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites.

• Authors : Mou M; Department of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.; College of Pharmaceutical Sciences, State Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang University, Hangzhou, China.

Subjects: Proteins*/Proteins*/Proteins*/chemistry ; Proteins*/Proteins*/Proteins*/metabolism ; Computational Biology*/Computational Biology*/Computational Biology*/methods

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Feb; Vol. 13 (10), pp. e16530. Date of Electronic Publication: 2025 Dec 27.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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PepLM-GNN: A graph neural network framework leveraging pre-trained language models for peptide-protein binding prediction.

• Authors : Yan K; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, China.; Zhongguancun Academy, Beijing, China.

Subjects: Peptides*/Peptides*/Peptides*/metabolism ; Peptides*/Peptides*/Peptides*/chemistry ; Computational Biology*/Computational Biology*/Computational Biology*/methods

• Source: PLoS computational biology [PLoS Comput Biol] 2026 Mar 24; Vol. 22 (3), pp. e1014084. Date of Electronic Publication: 2026 Mar 24 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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A Quantum Framework for Protein Binding-Site Structure Prediction on Utility-Level Quantum Processors.

• Authors : Zhang Y; Department of Computer Science, Kent State University, Kent, OH, 44240, USA.; Cleveland Clinic Genome Center, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, 44195, USA.

Subjects: Proteins*/Proteins*/Proteins*/chemistry ; Proteins*/Proteins*/Proteins*/metabolism ; Quantum Theory*

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Feb; Vol. 13 (12), pp. e13641. Date of Electronic Publication: 2025 Nov 28.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers.

• Authors : Sot J; Instituto Biofisika (UPV/EHU, CSIC), and Department of Biochemistry and Molecular Biology, University of the Basque Country, E-48940, Leioa, Spain.; Varela YR

Subjects: Lipid Bilayers*/Lipid Bilayers*/Lipid Bilayers*/metabolism ; Lipid Bilayers*/Lipid Bilayers*/Lipid Bilayers*/chemistry ; Oxazines*/Oxazines*/Oxazines*/chemistry

• Source: Scientific reports [Sci Rep] 2025 Oct 03; Vol. 15 (1), pp. 34571. Date of Electronic Publication: 2025 Oct 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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ProSiteHunter: A Unified Framework for Sequence-Based Prediction of Protein-Nucleic Acid and Protein-Protein Binding Sites.

• Authors : Hou D; College of Information Engineering, Zhejiang University of Technology, HangZhou, China.; Zhen Q

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Jun 02, pp. e75931. Date of Electronic Publication: 2026 Jun 02.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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GENEOnet: a breakthrough in protein binding pocket detection using group equivariant non-expansive operators.

• Authors : Bocchi G; Department of Environmental Science and Policy, Università degli Studi di Milano, Via Celoria 10, 20133, Milano, Italy. .; Frosini P

Subjects: Molecular Docking Simulation*/Molecular Docking Simulation*/Molecular Docking Simulation*/methods ; Proteins*/Proteins*/Proteins*/chemistry ; Proteins*/Proteins*/Proteins*/metabolism

• Source: Scientific reports [Sci Rep] 2025 Oct 03; Vol. 15 (1), pp. 34597. Date of Electronic Publication: 2025 Oct 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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RMDNet: RNA-aware dung beetle optimization-based multi-branch integration network for RNA-protein binding sites prediction.

• Authors : Zhang J; School of Computer Science and Technology, Hainan University, Haikou, 570100, Hainan, China.; Peng Y

Subjects: RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/metabolism ; RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/chemistry ; RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/genetics

• Source: BMC bioinformatics [BMC Bioinformatics] 2025 Jul 11; Vol. 26 (1), pp. 176. Date of Electronic Publication: 2025 Jul 11.Publisher: BioMed Central Country of Publication: England NLM ID: 100965194 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2105

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