Source: Bioorganic & Medicinal Chemistry : the tetrahedron journal for research at the interface of chemistry and biology, Vol. 20, no. 1, p. 58-68 (2012)

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The mTOR inhibitor RAD001 augments radiation-induced growth inhibition in a hepatocellular carcinoma cell line by increasing autophagy

Authors : UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie; UCL - (SLuc) Service de radiothérapie oncologique; Altmeyer, Anaïs

Subjects: Autophagy; Radiation-Sensitizing Agents; Sirolimus

Source: International Journal of Oncology, Vol. 41, no.4, p. 1381-1386 (2012)

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Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR

Authors : UCL - SSS/LDRI - Louvain Drug Research Institute; Kendall, Jackie D.; Giddens, Anna C.

Subjects: P110α; Benzenesulfonohydrazide; Hydrazide

Source: Bioorganic & Medicinal Chemistry : the tetrahedron journal for research at the interface of chemistry and biology, Vol. 20, no. 1, p. 58-68 (2012)

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Synthesis and biological evaluation of novel analogues of the pan class i phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(Difluoromethyl)-1-[4,6-di(4- morpholinyl)-1,3,5-triazin-2-yl]-1 H -benzimidazole (ZSTK474)

Authors : UCL - SSS/LDRI - Louvain Drug Research Institute; Rewcastle, Gordon W.; Gamage, Swarna A.

Subjects: 2 (2 difluoromethylbenzimidazol 1 yl) 4,6 dimorpholino 1,3,5 triazine; Female; Glioblastoma

Source: Journal of Medicinal Chemistry, Vol. 54, no.20, p. 7105-7126 (2011)

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Molecular regulation of human placental growth factor (PlGF) gene expression in placental villi and trophoblast cells is mediated via the protein kinase a pathway.

Authors : Emory University - School of Medicine; UCL - MD/GYPE - Département de gynécologie, d'obstétrique et de pédiatrie; Depoix, Christophe

Subjects: Cell Line, Tumor; Pregnancy Proteins; Pregnancy Trimester, First

Source: Reproductive Sciences, Vol. 18, no.3, p. 219-28 (2011)

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Regulation of transferrin receptor 2 in human cancer cell lines.

Authors : UCL - SSS/DDUV - Institut de Duve; Calzolari, Alessia; Finisguerra, Veronica

Subjects: Antigens, CD; Imatinib Mesylate; Iron

Source: Blood Cells, Molecules and Diseases, Vol. 42, no.1, p. 5-13 (2009)

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Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling

Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy.

Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment.

Role of PFKFB3-driven glycolysis in vessel sprouting.

Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR

The mTOR inhibitor RAD001 augments radiation-induced growth inhibition in a hepatocellular carcinoma cell line by increasing autophagy

Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR

Synthesis and biological evaluation of novel analogues of the pan class i phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(Difluoromethyl)-1-[4,6-di(4- morpholinyl)-1,3,5-triazin-2-yl]-1 H -benzimidazole (ZSTK474)

Molecular regulation of human placental growth factor (PlGF) gene expression in placental villi and trophoblast cells is mediated via the protein kinase a pathway.

Regulation of transferrin receptor 2 in human cancer cell lines.

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