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Academic Journal

UNified FramewOrk for reguLatory Dynamics (UNFOLD): Dissecting robustness, plasticity, evolvability and canalisation of biological function.

  • Authors : Chakraborty D; Bhupat and Jyoti Mehta School of Biosciences, Department of Biotechnology, Indian Institute of Technology (Madras), Chennai, India.; Centre for Integrative Biology and Systems medicinE (IBSE), IIT Madras, Chennai, India.

Subjects: Gene Regulatory Networks*/Gene Regulatory Networks*/Gene Regulatory Networks*/genetics ; Gene Expression Regulation*/Gene Expression Regulation*/Gene Expression Regulation*/genetics ; Models, Genetic*

  • Source: PLoS computational biology [PLoS Comput Biol] 2026 May 28; Vol. 22 (5), pp. e1014289. Date of Electronic Publication: 2026 May 28 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Decoupling between activation time and steady-state level in input-output responses.

  • Authors : Ravanelli G; CRG (Barcelona Collaboratorium for Modelling and Predictive Biology), Barcelona, Spain.; Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona Biomedical Research Park, Barcelona, Spain.

Subjects: Transcription Factors*/Transcription Factors*/Transcription Factors*/metabolism ; Transcription Factors*/Transcription Factors*/Transcription Factors*/genetics ; Gene Expression Regulation*/Gene Expression Regulation*/Gene Expression Regulation*/physiology

  • Source: PLoS computational biology [PLoS Comput Biol] 2026 May 15; Vol. 22 (5), pp. e1014288. Date of Electronic Publication: 2026 May 15 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Quantifying expression and metabolic activity of genes regulated by pregnane X receptor in primary human hepatocyte spheroids.

  • Authors : Lochman L; Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.; Kahiya ET

Subjects: Hepatocytes*/Hepatocytes*/Hepatocytes*/metabolism ; Pregnane X Receptor*/Pregnane X Receptor*/Pregnane X Receptor*/metabolism ; Spheroids, Cellular*/Spheroids, Cellular*/Spheroids, Cellular*/metabolism

  • Source: PLoS computational biology [PLoS Comput Biol] 2025 Apr 15; Vol. 21 (4), pp. e1012886. Date of Electronic Publication: 2025 Apr 15 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

High-Density Lipoproteins from Coronary Artery Disease and Aortic Valve Stenosis Patients Differentially Regulate Gene Expression in a Model of Cardiac Adipocytes.

  • Authors : Luna-Luna M; Department of Molecular Biology, Instituto Nacional de Cardiología 'Ignacio Chávez', Mexico City 14080, Mexico.; Páez A

Subjects: Aortic Valve Stenosis*/Aortic Valve Stenosis*/Aortic Valve Stenosis*/genetics ; Aortic Valve Stenosis*/Aortic Valve Stenosis*/Aortic Valve Stenosis*/metabolism ; Aortic Valve Stenosis*/Aortic Valve Stenosis*/Aortic Valve Stenosis*/blood

  • Source: Cells [Cells] 2025 Jan 30; Vol. 14 (3). Date of Electronic Publication: 2025 Jan 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Osthole Inhibits Expression of Genes Associated with Toll-like Receptor 2 Signaling Pathway in an Organotypic 3D Skin Model of Human Epidermis with Atopic Dermatitis.

  • Authors : Kordulewska NK; Department of Biochemistry, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.; Topa J

Subjects: Gene Expression Regulation*/Gene Expression Regulation*/Gene Expression Regulation*/drug effects ; Signal Transduction*/Signal Transduction*/Signal Transduction*/genetics ; Models, Biological*

  • Source: Cells [Cells] 2021 Dec 28; Vol. 11 (1). Date of Electronic Publication: 2021 Dec 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

A spatio-temporal model to reveal oscillator phenotypes in molecular clocks: Parameter estimation elucidates circadian gene transcription dynamics in single-cells.

  • Authors : Unosson M; Department of Statistics, University of Warwick, Coventry, United Kingdom.; Brancaccio M

Subjects: Circadian Rhythm Signaling Peptides and Proteins*/Circadian Rhythm Signaling Peptides and Proteins*/Circadian Rhythm Signaling Peptides and Proteins*/genetics ; Circadian Rhythm Signaling Peptides and Proteins*/Circadian Rhythm Signaling Peptides and Proteins*/Circadian Rhythm Signaling Peptides and Proteins*/metabolism ; Models, Biological*

  • Source: PLoS computational biology [PLoS Comput Biol] 2021 Dec 17; Vol. 17 (12), pp. e1009698. Date of Electronic Publication: 2021 Dec 17 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Biological features between miRNAs and their targets are unveiled from deep learning models.

  • Authors : Gu T; Bioinformatics, Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL, USA. .; Division of Quantitative Sciences, University of Florida Health Cancer Center, University of Florida, 2033 Mowry Road, Gainesville, FL, 32610, USA. .

Subjects: Deep Learning* ; Gene Expression Regulation* ; Models, Biological*

  • Source: Scientific reports [Sci Rep] 2021 Dec 10; Vol. 11 (1), pp. 23825. Date of Electronic Publication: 2021 Dec 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A Distinctive NAFLD Signature in Adipose Tissue from Women with Severe Obesity.

  • Authors : Osorio-Conles Ó; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Rosselló Street 149, 08036 Barcelona, Spain.; Vega-Beyhart A

Subjects: Gene Expression Regulation* ; Models, Biological*; Adipokines/Adipokines/Adipokines/*biosynthesis

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 29; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A Modular Mathematical Model of Exercise-Induced Changes in Metabolism, Signaling, and Gene Expression in Human Skeletal Muscle.

  • Authors : Akberdin IR; Department of Computational Biology, Scientific Center for Information Technologies and Artificial Intelligence, Sirius University of Science and Technology, 354340 Sochi, Russia.; BIOSOFT.RU, LLC, 630090 Novosibirsk, Russia.

Subjects: Calcium Signaling* ; Energy Metabolism* ; Exercise*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 26; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

B6-Dct-H2BGFP bitransgenic mice: A standardized mouse model for in vivo characterization of melanocyte development and stem cell differentiation.

  • Authors : Tandukar B; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.; Kalapurakal E

Subjects: Cell Differentiation* ; Gene Expression Regulation* ; Models, Biological*

  • Source: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2021 Sep; Vol. 34 (5), pp. 905-917. Date of Electronic Publication: 2021 May 18.Publisher: Blackwell Munksgaard Country of Publication: England NLM ID: 101318927 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  2,533 results for ""Models, Biological""