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Academic Journal

Multiple Primary Lung Cancer With Driver Gene Mutations: Is Targeted Therapy Always the Optimal Choice?-A Case Report.

  • Authors : Ren ZR; Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.; Wu L

Subjects: Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/diagnostic imaging ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/genetics

  • Source: Thoracic cancer [Thorac Cancer] 2026 Jan; Vol. 17 (1), pp. e70215.Publisher: Wiley Publishing Asia Pty Ltd Country of Publication: Singapore NLM ID: 101531441 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Deep learning radiopathomics predicts targeted therapy sensitivity in EGFR-mutant lung adenocarcinoma.

  • Authors : Yang T; Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038, China.; Yu-Yue Pathology Scientific Research Center, Chongqing, 400039, China.

Subjects: Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/genetics ; Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/diagnostic imaging ; Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/drug therapy

  • Source: Journal of translational medicine [J Transl Med] 2025 Apr 29; Vol. 23 (1), pp. 482. Date of Electronic Publication: 2025 Apr 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

BRAF mutations and targeted therapy in unclassified pericytic tumors: insights from genetic analysis and clinical response.

  • Authors : Golan H; Division of Pediatric Hematology and Oncology, Cancer Research Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 52620, Israel. .; School of Medicine, Gray Faculty of Medical and Health Sciences, Tel-Aviv University, Tel- Aviv, 6997801, Israel. .

Subjects: Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/genetics ; Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/antagonists & inhibitors ; Hemangiopericytoma*/Hemangiopericytoma*/Hemangiopericytoma*/genetics

  • Source: BMC cancer [BMC Cancer] 2025 Oct 31; Vol. 25 (1), pp. 1685. Date of Electronic Publication: 2025 Oct 31.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

[Expert consensus on the diagnosis and treatment of advanced non-small cell lung cancer with EGFR PACC mutations (2025 edition)].

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/diagnosis

  • Source: Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2025 Sep 23; Vol. 47 (9), pp. 811-829.Publisher: Chinese Medical Association Country of Publication: China NLM ID: 7910681 Publication Model: Print Cited Medium: Print ISSN: 0253-3766

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Academic Journal

Novel therapeutic strategies for rare mutations in non-small cell lung cancer.

  • Authors : Gou Q; Department of Radiation Oncology and Department of Head & Neck Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Gou Q

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/genetics

  • Source: Scientific reports [Sci Rep] 2024 May 05; Vol. 14 (1), pp. 10317. Date of Electronic Publication: 2024 May 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Evaluating targeted therapies in older patients with TP53-mutated AML.

  • Authors : Sabile JMG; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.; Division of Hematology & Medical Oncology, Department of Medicine, Oregon Health & Science University, Portland, OR, USA.

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/therapy

  • Source: Leukemia & lymphoma [Leuk Lymphoma] 2024 Sep; Vol. 65 (9), pp. 1201-1218. Date of Electronic Publication: 2024 Apr 22.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Clinical Impact of TP53 Mutations in Patients with Head and Neck Cancer Who Were Treated with Targeted Therapies or Immunotherapy.

  • Authors : Kang EJ; Division of Hemato-oncology, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.; Hwang S

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/genetics ; Head and Neck Neoplasms*/Head and Neck Neoplasms*/Head and Neck Neoplasms*/genetics ; Head and Neck Neoplasms*/Head and Neck Neoplasms*/Head and Neck Neoplasms*/drug therapy

  • Source: Cancer research and treatment [Cancer Res Treat] 2025 Jul; Vol. 57 (3), pp. 709-719. Date of Electronic Publication: 2024 Dec 23.Publisher: Korean Cancer Association Country of Publication: Korea (South) NLM ID: 101155137 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Liquid-based cytology specimens for next-generation sequencing in lung adenocarcinoma: challenges and evaluation of targeted therapy.

  • Authors : Xiao X; Cytopathology Section, Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.; Sun Z

Subjects: Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/genetics ; Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/drug therapy ; Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/Adenocarcinoma of Lung*/pathology

  • Source: BMC cancer [BMC Cancer] 2024 Jun 20; Vol. 24 (1), pp. 749. Date of Electronic Publication: 2024 Jun 20.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Mutational Landscape Assessed in Tumor Tissue and Circulating Tumor DNA During Treatment of Patients with HER2/ERBB2-Mutated Solid Tumors.

  • Authors : Egebjerg K; Department of Oncology, Copenhagen University Hospital, Rigshospitalet, 9, Blegdamsvej, Copenhagen, 2100, Denmark. .; Spanggaard I

Subjects: Erb-b2 Receptor Tyrosine Kinases*/Erb-b2 Receptor Tyrosine Kinases*/Erb-b2 Receptor Tyrosine Kinases*/genetics ; Erb-b2 Receptor Tyrosine Kinases*/Erb-b2 Receptor Tyrosine Kinases*/Erb-b2 Receptor Tyrosine Kinases*/antagonists & inhibitors ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

  • Source: BMC cancer [BMC Cancer] 2025 Aug 06; Vol. 25 (1), pp. 1272. Date of Electronic Publication: 2025 Aug 06.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Mutant p53 as a Therapeutic Target: The Report of Its Death Was an Exaggeration.

  • Authors : Toledo F; Hematopoietic and Leukemic Development Team, Centre de Recherche Saint-Antoine, 75012 Paris, France.; INSERM UMRS938, 75012 Paris, France.

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/genetics ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/antagonists & inhibitors

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 04; Vol. 26 (13). Date of Electronic Publication: 2025 Jul 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  843 results for ""Molecular Targeted Therapy""