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Academic Journal

Computational and experimental discovery of peptide inhibitors targeting survivin for therapeutic potential in cancer.

  • Authors : Ahmadi SF; Department of Biology, CT.C. Islamic Azad University, Tehran, Iran.; Arab SS

Subjects: Survivin*/Survivin*/Survivin*/antagonists & inhibitors ; Survivin*/Survivin*/Survivin*/metabolism ; Survivin*/Survivin*/Survivin*/chemistry

  • Source: Scientific reports [Sci Rep] 2025 Aug 20; Vol. 15 (1), pp. 30599. Date of Electronic Publication: 2025 Aug 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Second Mitochondria-Derived Activator of Caspases Mimetic BI 891065 in Patients With Advanced Solid Tumors: Results From Two Phase I Studies.

  • Authors : Patel MR; Florida Cancer Specialists/Sarah Cannon Research Institute, Sarasota, Florida, USA.; Hamilton EP

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/pathology ; Neoplasms*/Neoplasms*/Neoplasms*/metabolism

  • Source: Cancer medicine [Cancer Med] 2025 Dec; Vol. 14 (24), pp. e71451.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Targeting Inhibitor of Apoptosis Proteins to Overcome Chemotherapy Resistance-A Marriage between Targeted Therapy and Cytotoxic Chemotherapy.

  • Authors : Barroso T; Medical Oncology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, 1649-035 Lisbon, Portugal.; Melo-Alvim C

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Radiation Oncology*; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 29; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Overview of role of survivin in cancer: expression, regulation, functions, and its potential as a therapeutic target.

  • Authors : Fang XL; Academician Expert Workstation of Fengxian District, Shanghai Yuansong Biotechnology Limited Company, Shanghai, China.; Cao XP

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy; Survivin/Survivin/Survivin/therapeutic use ; Inhibitor of Apoptosis Proteins/Inhibitor of Apoptosis Proteins/Inhibitor of Apoptosis Proteins/genetics

  • Source: Journal of drug targeting [J Drug Target] 2024 Dec; Vol. 32 (3), pp. 223-240. Date of Electronic Publication: 2024 Feb 01.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9312476 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A phase I study of LCL161, a novel oral pan-inhibitor of apoptosis protein (IAP) antagonist, in Japanese patients with advanced solid tumors.

  • Authors : Morita S; Department of Clinical Oncology and Chemotherapy, Nagoya University Hospital, Nagoya, Japan.; Minami H

Subjects: Inhibitor of Apoptosis Proteins*/Inhibitor of Apoptosis Proteins*/Inhibitor of Apoptosis Proteins*/administration & dosage ; Inhibitor of Apoptosis Proteins*/Inhibitor of Apoptosis Proteins*/Inhibitor of Apoptosis Proteins*/antagonists & inhibitors ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: Asia-Pacific journal of clinical oncology [Asia Pac J Clin Oncol] 2022 Oct; Vol. 18 (5), pp. e427-e434. Date of Electronic Publication: 2022 Jan 30.Publisher: Blackwell Pub. Asia Country of Publication: Australia NLM ID: 101241430 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Potency and Selectivity of SMAC/DIABLO Mimetics in Solid Tumor Therapy.

  • Authors : Zhao XY; Laboratory of Cancer Biology and Epigenetics, Department of Cell Biology and Genetics, Shantou University Medical College, Shantou, Guangdong 515041, China.; Wang XY

Subjects: Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*metabolism ; Inhibitor of Apoptosis Proteins/Inhibitor of Apoptosis Proteins/Inhibitor of Apoptosis Proteins/*pharmacology ; Mitochondria/Mitochondria/Mitochondria/*drug effects

  • Source: Cells [Cells] 2020 Apr 18; Vol. 9 (4). Date of Electronic Publication: 2020 Apr 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

The Immuno-Modulatory Effects of Inhibitor of Apoptosis Protein Antagonists in Cancer Immunotherapy.

  • Authors : Michie J; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, VIC 3010, Australia.

Subjects: Immunotherapy*; Immunologic Factors/Immunologic Factors/Immunologic Factors/*pharmacology ; Inhibitor of Apoptosis Proteins/Inhibitor of Apoptosis Proteins/Inhibitor of Apoptosis Proteins/*antagonists & inhibitors

  • Source: Cells [Cells] 2020 Jan 14; Vol. 9 (1). Date of Electronic Publication: 2020 Jan 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Comprehensive molecular characterization of inhibitors of apoptosis proteins (IAPs) for therapeutic targeting in cancer.

  • Authors : Liang J; Department of Neurosurgery, Peking University International Hospital, 1 Science Park Road, ZGC Life Science Park, Beijing, 102206, China.; Zhao W

Subjects: Inhibitor of Apoptosis Proteins*/Inhibitor of Apoptosis Proteins*/Inhibitor of Apoptosis Proteins*/genetics ; Inhibitor of Apoptosis Proteins*/Inhibitor of Apoptosis Proteins*/Inhibitor of Apoptosis Proteins*/metabolism ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: BMC medical genomics [BMC Med Genomics] 2020 Jan 21; Vol. 13 (1), pp. 7. Date of Electronic Publication: 2020 Jan 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium: Internet ISSN: 1755-8794

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Academic Journal

Survivin Small Molecules Inhibitors: Recent Advances and Challenges.

  • Authors : Albadari N; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, USA.; Li W

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 01; Vol. 28 (3). Date of Electronic Publication: 2023 Feb 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

New Class of Benzodiazepinone Derivatives as Pro-Death Agents Targeting BIR Domains in Cancer Cells.

  • Authors : Fiore M; National Research Council (IBF-CNR) Genoa Unit, Institute of Biophysics, Via De Marini 6, 16149 Genova, Italy.; Mosconi M

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Neoplasms*; NF-kappa B/NF-kappa B/NF-kappa B/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2023 Jan 03; Vol. 28 (1). Date of Electronic Publication: 2023 Jan 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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  • 1-10 of  166 results for ""Inhibitor of Apoptosis Proteins""