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Efficacy of Remibrutinib versus Dupilumab at Early Timepoints in Chronic Spontaneous Urticaria: US Phase 3b Study Design (RECLAIM)

• Authors : Yosipovitch, Gil¹ (AUTHOR) ; Mosnaim, Giselle² (AUTHOR); Ortmann, Christine-Elke³ (AUTHOR)

• Source: Dermatology & Therapy. Mar2026, p1-11. 11p.

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ILOBONE: A phase I/IIa randomized controlled trial to assess the safety and feasibility of local iloprost therapy for enhancing proximal humerus fracture healing– a pilot study design.

• Authors : Elazaly, Hisham^1,2,3; Dimitriou, Ioanna Maria^2,3,4; Maleitzke, Tazio^1,2,5,6,7

• Source: Journal of Orthopaedic Surgery & Research. 5/22/2025, Vol. 20 Issue 1, p1-10. 10p.

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Can Early Use of HFNC through Improved Study Design Make a Statistically Significant Difference in the Rate of Intubation in Patients with Post-traumatic Lung Contusion?

• Authors : Sharma, Sachit¹ ; Shrestha, Pramesh S.¹; Acharya, Subhash P.¹

• Source: Indian Journal of Critical Care Medicine. Apr2025, Vol. 29 Issue 4, p396-399. 4p.

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Study Design and Protocol for a Randomized Controlled Trial of Enavogliflozin to Evaluate Cardiorenal Outcomes in Type 2 Diabetes (ENVELOP).

• Authors : Nam Hoon Kim¹; Soo Lim²; In-Kyung Jeong³

• Source: Diabetes & Metabolism Journal. Mar2025, Vol. 49 Issue 2, p225-234. 16p.

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Impact of diagnosis-related group payment on medical expenditure and treatment efficiency on people with drug-resistant tuberculosis: a quasi-experimental study design.

• Authors : Xiong, Yingbei¹; Yao, Yifan¹; Li, Yuehua²

• Source: International Journal for Equity in Health. 1/2/2025, Vol. 24 Issue 1, p1-10. 10p.

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Short term effectiveness of ustekinumab versus vedolizumab in Crohn's disease after failure of anti-TNF agents: An observational comparative study design with a Bayesian analysis.

• Authors : Alamer, Ahmad¹ ; Al Lehaibi, Lina H²; Alomar, Mukhtar²

Subjects: *Therapeutic use of monoclonal antibodies; *Anti-inflammatory agents; *Crohn's diseaseSaudi Arabia

• Source: Saudi Journal of Gastroenterology. Sep/Oct2024, Vol. 30 Issue 5, p324-334. 11p.

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Exploring Study Design Foibles in Randomized Controlled Trials on Convalescent Plasma in Hospitalized COVID-19 Patients.

• Authors : Franchini, Massimo¹ (AUTHOR) ; Mengoli, Carlo¹ (AUTHOR); Casadevall, Arturo² (AUTHOR)

• Source: Life (2075-1729). Jul2024, Vol. 14 Issue 7, p792. 14p.

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Analysis: Study design contributed to differences in ketamine‐ECT trials.

• Source: Brown University Psychopharmacology Update. Jun2024, Vol. 35 Issue 6, p1-5. 5p.

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A general framework to support cost-efficient fecal egg count methods and study design choices for large-scale STH deworming programs–monitoring of therapeutic drug efficacy as a case study.

• Authors : Coffeng, Luc E.¹ (AUTHOR) ; Vlaminck, Johnny² (AUTHOR); Cools, Piet³ (AUTHOR)

• Source: PLoS Neglected Tropical Diseases. 5/17/2023, Vol. 16 Issue 5, p1-23. 23p.

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Staged or Simultaneous Surgery for Colon or Rectal Cancer with Synchronous Liver Metastases: Implications for Study Design and Clinical Endpoints.

• Authors : Yaqub, Sheraz^1,2 (AUTHOR) ; Margonis, Georgios Antonios³ (AUTHOR); Søreide, Kjetil^4,5 (AUTHOR)

• Source: Cancers. Apr2023, Vol. 15 Issue 7, p2177. 9p.

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