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Lock, Protect, and Bind: In Vitro Selection of Locked Nucleic Acid‐Modified Aptamers Using a Mutant T7 RNA Polymerase.

• Authors : Neis, Kevin¹ (AUTHOR); Civit, Laia¹ (AUTHOR); Pedersen, Kathrine² (AUTHOR)

• Source: Small Structures. Mar2026, Vol. 7 Issue 3, p1-14. 14p.

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Locked nucleic acid (LNA) based PCR approach for the diagnosis and screening of spinal muscular atrophy.

• Authors : Amuran, Gökçe Güllü^1,2 (AUTHOR) ; Polat, Büşra^1,2 (AUTHOR); Türkdoğan, Dilşad³ (AUTHOR)

• Source: Indian Journal of Medical Research. Feb2026, Vol. 163 Issue 2, p1-8. 8p.

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Cycloalkane Incorporation Into the 2′,4′-Bridge of Locked Nucleic Acid: Enhancing Nuclease Stability, Reducing Phosphorothioate Modifications, and Lowering Hepatotoxicity in Antisense Oligonucleotides

• Authors : Takao Yamaguchi; Hibiki Komine; Takaya Sugiura

Subjects: Chemistry; QD1-999

• Source: JACS Au, Vol 5, Iss 10, Pp 5111-5120 (2025)

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Physical Adsorption‐Driven Assembly of Au‐Locked Nucleic Acid (LNA) Probes on MoS2 Nanosheets for SERS‐Based Detection of microRNAs (miRNAs)

• Authors : Faith Mokobi Zablon; Md. Arifur Rahman Khan; Tetyana Ignatova

Subjects: Cy3; LNAs; miRNA

• Source: Advanced Materials Interfaces, Vol 12, Iss 23, Pp n/a-n/a (2025)

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Locked nucleic acid-modified antisense oligonucleotides attenuate scar hyperplasia through targeted inhibition of CTGF

• Authors : Jinhe Li; Xi Wu; Ying Yang

Subjects: CTGF; antisense oligonucleotide; scar

• Source: Frontiers in Pharmacology, Vol 16 (2025)

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The free energy of locking a ring: Changing a deoxyribonucleoside to a locked nucleic acid

• Authors : Xu, Y, Author; Villa, A, Author; Nilsson, L, Author ...

• Source: JOURNAL OF COMPUTATIONAL CHEMISTRY. 38(15):1147-1157

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Imprinting analysis by droplet digital PCR coupled with locked nucleic acid TaqMan probes

• Authors : Maiko Mitake; Shiori Hirano; Tatsuya Kishino

Subjects: genomic imprinting; droplet digital pcr; locked nucleic acid

• Source: Epigenetics, Vol 16, Iss 7, Pp 729-740 (2021)

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Development of a duplex qPCR assay with locked nucleic acid probes for A, B and E kappa-casein variants detection

• Authors : L. Jiménez-Montenegro; J. A. Mendizabal; L. Alfonso ...

Subjects: 0301 basic medicine; 2. Zero hunger; 0303 health sciences

• Source: Sci RepAcademica-e. Repositorio Institucional de la Universidad Pública de NavarraUniversidad Pública de NavarraScientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

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Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

• Authors : Moreno, PMD, Author; Geny, S, Author; Pabon, YV, Author ...

• Source: NUCLEIC ACIDS RESEARCH. 41(5):3257-3273

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Targeting murine alveolar macrophages by the intratracheal administration of locked nucleic acid containing antisense oligonucleotides

• Authors : Yasunori Uemura; Katsuya Kobayashi

Subjects: 0301 basic medicine; 0303 health sciences; Injection, Intratympanic

• Source: Drug DelivDrug Delivery, Vol 26, Iss 1, Pp 803-811 (2019)

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