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Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli.

• Authors : Koch, Nikolaj G.^1,2,3,4 (AUTHOR); Goettig, Peter⁵ (AUTHOR); Nash, Michael A.^3,4 (AUTHOR)

• Source: Advanced Science. Apr2026, p1. 15p. 7 Illustrations.

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Identification of an uncharacterized gene as a mitochondrial methionine tRNA synthetase in Caenorhabditis elegans.

• Authors : Thapa, Bharat Vivan¹ (AUTHOR); Das, Mohit² (AUTHOR); Taylor, David I² (AUTHOR)

• Source: G3: Genes | Genomes | Genetics. Feb2026, Vol. 16 Issue 2, p1-12. 12p.

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Mycoplasma penetrans methionyl-tRNA synthetase dimerizes via tandem N-terminal ancillary domains.

• Authors : Ghazi Esfahani B; Department of Biological Science, Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida, United States of America.; Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, United Stated of America.

Subjects: Methionine-tRNA Ligase*/Methionine-tRNA Ligase*/Methionine-tRNA Ligase*/chemistry ; Methionine-tRNA Ligase*/Methionine-tRNA Ligase*/Methionine-tRNA Ligase*/metabolism ; Methionine-tRNA Ligase*/Methionine-tRNA Ligase*/Methionine-tRNA Ligase*/genetics

• Source: PloS one [PLoS One] 2026 May 27; Vol. 21 (5), pp. e0347747. Date of Electronic Publication: 2026 May 27 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Sod1-deficient cells are impaired in formation of the modified nucleosides mcm5s2U and yW in tRNA

• Authors : Xu, Fu, Author; Byström, Anders, Author; Johansson, Marcus J. O., Author ...

Subjects: iron-sulfur cluster; modified nucleosides; oxidative stress

• Source: RNA. 30(12):1586-1595

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Repressive regulatory function of seryl-tRNA synthetase on VEGFA gene expression is impaired in renal cell carcinoma.

• Authors : Barači M; Ozretić P; Knezovic Florijan M

Subjects: Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/genetics ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/metabolism ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/pathology

• Source: Croatian medical journal [Croat Med J] 2026 Apr 30; Vol. 67 (2), pp. 72-84.Publisher: Medicinska Naklada Country of Publication: Croatia NLM ID: 9424324 Publication Model: Print Cited Medium: Internet ISSN: 1332-8166

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Menstrual cycle-dependent expression of tRNA-derived fragments in healthy human endometrium and uterine fluid-derived extracellular vesicles

• Authors : Apostolov, A, Author; Naydenov, M, Author; Kambareva, K, Author ...

• Source: BMC GENOMICS. 27(1)

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Prolyl tRNA Synthetase Is Required for Mammarenavirus Multiplication.

• Authors : Witwit, Haydar¹ (AUTHOR); Ibanez, Pablo^1,2 (AUTHOR); Zhou, Ruifeng¹ (AUTHOR)

• Source: Viruses (1999-4915). Feb2026, Vol. 18 Issue 2, p202. 20p.

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Novel tRNA Synthetase Inhibitors Increase Healthspan, Lifespan, and Autophagic Flux in C. elegans.

• Authors : Heath OC; Department of Biochemistry and Molecular Biology, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.; Otero MP

Subjects: Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/drug effects ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/physiology ; Autophagy*/Autophagy*/Autophagy*/drug effects

• Source: Biomolecules [Biomolecules] 2026 Jan 01; Vol. 16 (1). Date of Electronic Publication: 2026 Jan 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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WDR5-H3K4me3 Epigenetic Axis Promotes TRMT6-Dependent tRNA M1A Modification to Facilitate Triple-Negative Breast Cancer Progression by Suppressing Ferroptosis.

• Authors : Lei Y; Department of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, 450008, China.; Wang X

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/genetics ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Feb; Vol. 13 (11), pp. e13277. Date of Electronic Publication: 2025 Dec 14.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Evaluation of Serum FGF21 Levels in Patients with Mitochondrial Aminoacyl-tRNA Synthetase Deficiency.

• Authors : Tekin Neijmann, Sebnem¹ (AUTHOR); Gunes, Dilek² (AUTHOR); Karaca, Meryem^2,3 (AUTHOR)

• Source: International Journal of Molecular Sciences. Oct2025, Vol. 26 Issue 19, p9525. 9p.

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