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Vitiligo, Melasma, PIH, and Albinism.

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Author(s): Urbonas, Rebecca; Jilani, Sumrah; Cohen, Bernard A.
Source:
Dermatology Times. Feb2025, Vol. 46 Issue 2, p14-16. 3p.

Additional Information
- Subject Terms:
  ALBINISM; NF-kappa B; MICRONEEDLING; SKIN tumors; VITILIGO; PIGMENTATION disorders; PLATELET-rich plasma; JANUS kinases; PHOTOTHERAPY; LASER therapy; TACROLIMUS; QUALITY of life; NEUROTRANSMITTER uptake inhibitors; TRANEXAMIC acid; MELANOSIS; HYPERPIGMENTATION; WELL-being; SOCIAL stigma; CHEMICAL inhibitors; CHILDREN
- Abstract:
  The article reviews emerging therapies for pigmentary disorders and their challenges as of February 2025. Topics discussed include the efficacy of topical tacrolimus in infants, and of JAK1/2 inhibitor ruxolitinib cream for skin repigments in vitiligo, and the potential of the NF-kB inhibitor Bay 11-7082 to suppress postinflammatory hyperpigmentation (PH). Also noted is the effectivity of sunscreens with iron oxide in reducing pigment, and of thiamidol and tranexamic acid (TXA) in melasma.

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