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Isolates and antibiotic sensitivity of eighty culture-proven endophthalmitis cases from Istanbul.
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- Author(s): Eser I;Eser I; Kapran Z; Altan T; Ozel Karatas M; Aydin D; Okaygun E; Yilmaz OF
- Source:
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde [Ophthalmologica] 2008; Vol. 222 (3), pp. 157-60. Date of Electronic Publication: 2008 May 22.
- Publication Type:
Comparative Study; Journal Article
- Language:
English
- Additional Information
- Source:
Publisher: Karger Country of Publication: Switzerland NLM ID: 0054655 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0267 (Electronic) Linking ISSN: 00303755 NLM ISO Abbreviation: Ophthalmologica Subsets: MEDLINE
- Publication Information:
Publication: Basel : Karger
Original Publication: Basel.
- Subject Terms:
- Abstract:
Purpose: To investigate the spectrum of organisms causing endophthalmitis and their sensitivity to commonly used antimicrobial agents.
Methods: Medical records of 80 consecutive patients treated at Beyoglu Eye Hospital for endophthalmitis from January 2001 to April 2006 were reviewed. Specimens were obtained from either the vitreous (93%, 81/87) or anterior chamber (7%, 6/87) during pars plana vitrectomy or vitreous tap, and were inoculated into blood culture bottles. A Kirby-Bauer disk diffusion test was performed to determine antibiotic susceptibility. The outcome measures included isolates identified and antibiotic sensitivity of the specimens.
Results: Fifty-six of 87 (64.4%) isolates were Gram-positive organisms, 29 (33.3%) were Gram-negative organisms, and 2 (2.3%) were fungi. The most common organism group identified was coagulase-negative staphylococci in 26.4% (23/87). While vancomycin was active against all Gram-positive isolates tested (100%), ceftazidime had the highest susceptibility rate (100%) for Gram-negative organisms isolated.
Conclusions: Although coagulase-negative micrococci predominated in this series, a high isolation rate for Gram-negative organisms was obtained. High susceptibility rates for ofloxacin make it an alternative to ceftazidime and vancomycin in both Gram-negative- and Gram-positive-derived endophthalmitis, respectively. Studies with larger series and additional antibiotics are needed to confirm these findings.
((c) 2008 S. Karger AG, Basel)
- Accession Number:
0 (Anti-Bacterial Agents)
- Publication Date:
Date Created: 20080524 Date Completed: 20080703 Latest Revision: 20080523
- Publication Date:
20250114
- Accession Number:
10.1159/000126077
- Accession Number:
18497523
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