Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease.

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Author(s): Assmus, Frauke^1,2 (AUTHOR); Adehin, Ayorinde^1,2 (AUTHOR); Hoglund, Richard M.^1,2 (AUTHOR); Fortes Francisco, Amanda³ (AUTHOR); Lewis, Michael D.^3,4 (AUTHOR); Kelly, John M.³ (AUTHOR); Charman, Susan A.⁵ (AUTHOR); White, Karen L.⁵ (AUTHOR); Shackleford, David M.⁵ (AUTHOR); Escudié, Fanny⁶ (AUTHOR); Chatelain, Eric⁶ (AUTHOR); Scandale, Ivan⁶ (AUTHOR); Tarning, Joel^1,2 (AUTHOR)
Source:
PLoS Neglected Tropical Diseases. 5/13/2025, Vol. 19 Issue 5, p1-22. 22p.