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Impact of Diabetic Retinopathy Treatment Modalities on Vision-Related Quality of Life: A Comparative Study Using NEI VFQ-25.

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    • Subject Terms:
      National Eye Institute
    • Abstract:
      المقال يركز على دراسة مقارنة تقيم تأثير أساليب علاج اعتلال الشبكية السكري (DR) المختلفة على جودة الحياة المتعلقة بالرؤية (VR-QOL) باستخدام استبيان وظيفة الرؤية من المعهد الوطني للعيون (NEI VFQ-25). أجريت الدراسة في مركز المنصورة لطب العيون، وشملت 200 مريض تم تقسيمهم إلى أربع مجموعات علاجية: التخثير الضوئي بالليزر، حقن مضادات VEGF، الستيرويدات داخل الجسم الزجاجي، واستئصال الزجاجية. أظهرت النتائج أن جميع أساليب العلاج حسنت بشكل كبير من جودة الحياة المتعلقة بالرؤية، حيث أظهر استئصال الزجاجية التأثير الأكثر أهمية، خاصة في الحالات المتقدمة من اعتلال الشبكية السكري. تؤكد النتائج على أهمية اتباع أساليب علاج شخصية بناءً على شدة المرض لتحسين نتائج المرضى. [Extracted from the article]
    • Abstract:
      Background: Diabetic retinopathy (DR) is a leading cause of visual impairment and affects patients' quality of life. Understanding the impact of different treatments on vision-related quality of life (VR-QOL) is essential for optimizing care. Objective: To assess the effect of different lines of diabetic retinopathy treatment on patients' (VR-QOL) using the National Eye Institute Visual Function Questionnaire (NEI VFQ-25). Patients and Methods: This prospective quasi-experimental study was conducted in Mansoura Ophthalmology Center over 6 months on 200 diabetic retinopathy patients, in which 50 patients received laser photocoagulation, 50 patients received anti-VEGF treatment, 50 received intravitreal steroids, and vitrectomy was planned for 50 patients. The NEI VFQ-25 was fulfilled by all patients before treatment and 1 month and 6 months after treatment. The results were compared to the baseline in each group. Results: The mean age of the included patients was 57.58±7.38 years with female predominance (54.5%). Patients who underwent vitrectomy had significantly higher mean age compared to patients who received laser or anti-VEGF therapy and most of them came from rural areas. Most of the subscales and total score showed significant improvement from baseline to 1- month and 6- month post treatment in total cohort. The most significant improvement was noted in the vitrectomy group followed by the anti-VEGF group. Conclusion: All treatment modalities led to significant improvements in VR-QOL with varying degrees. Vitrectomy demonstrated the most substantial effect, particularly in advanced DR, followed by intravitreal anti-VEGF. The study highlights the importance of tailored interventions based on disease severity. [ABSTRACT FROM AUTHOR]
    • Abstract:
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