Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

ارتباط بین سطح سرمی اینترلوکین - ۴۱ و وضعیت سرطان پستان یک مطالعه مورد شاهدی از زنان عراقی.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read Online Read More Add to Saved list
  • Additional Information
    • Alternate Title:
      Association Between Serum Interleukin-41 Levels and Breast Cancer Status: A Case–Control Study in Iraqi Women.
    • Subject Terms:
      Iraq
    • Abstract:
      Introduction: Breast cancer is the most common malignancy among women worldwide. Interleukin-41 (IL-41) is a novel cytokine with immunomodulatory functions. This study aimed to evaluate serum IL-41 levels in breast cancer patients compared with healthy women. Methods: A case–control study was conducted on 60 breast cancer patients (20– 41 y) and 30 healthy age-matched women (20–40 y) recruited from the Teaching Oncology Hospital, Baghdad (Dec 2023–Mar 2024). Demographic data were recorded. Serum IL-41 was measured using ELISA; liver enzymes GOT and GPT were assessed by spectrophotometry. Mann–Whitney U test and Cliff’s delta were used for analysis. Results: Median IL-41 levels were significantly higher in patients compared to controls (p<0.001, Δ=0.75; p=0.002, Δ=0.80). GPT was also elevated in patients (p=0.004, Δ=0.45; p=0.01, Δ=0.60), while GOT showed no significant difference (p>0.05). Conclusion: IL-41 may serve as a promising biomarker for breast cancer independent of age. Elevated GPT may indicate hepatic involvement. Further studies are required to validate these findings. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Iranian Journal of Breast Diseases is the property of Iranian Journal of Breast Diseases and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)