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Lack of patient education is risk factor of disease flare in patients with systemic lupus erythematosus in China.

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  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101088677 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6963 (Electronic) Linking ISSN: 14726963 NLM ISO Abbreviation: BMC Health Serv Res Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, [2001-
    • Subject Terms:
      Patient Education as Topic* ; Drug Monitoring*; Health Literacy/*statistics & numerical data ; Lupus Erythematosus, Systemic/*therapy; Lupus Erythematosus, Systemic/complications ; Adult ; China ; Cross-Sectional Studies ; Disease Management ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Quality of Life ; Risk Factors ; Self Report
    • Abstract:
      Background: To explore the inadequacies of health service and its impact on clinical outcomes of patients with systemic lupus erythematosus (SLE) in China.
      Methods: A total of 210 SLE patients were randomly recruited between January 2017 and January 2018. Each patient received self-report questionnaires to assess medication adherence [Compliance Questionnaire for Rheumatology (CQR)], beliefs about medicines [Beliefs about Medicines Questionnaire (BMQ)] and satisfaction about medicine information [the Satisfaction with Information about Medicines Scale (SIMS)]. Associations between SLE disease activity index (SLEDAI-2 K) and observed factors were analyzed by multiple logistic regression.
      Results: Based on CQR, only 28.10% patients were adherent. The score of BMQ was 2.85 ± 5.42, and merely 32.38% patients were satisfied with the information about their prescribed medicines. Disease activity was associated with SIMS, EuroQol five-dimensions [EQ5D], Systemic Lupus International Collaborating Clinics (SLICC), depression, use of NSAID (P ≤ 0.05). Remission of disease was positively correlated with SIMS (OR = 0.16, 95% CI: [0.06, 0.40]), and BMQ (OR = 0.64, 95%CI: [0.43, 0.94]).
      Conclusion: In this study, the scores of BMQ and SIMS were low, implying defects in the patient education of health service system, which led to disease flare in Chinese SLE patients.
      Trial Registration: ClinicalTrials.gov ID: NCT03024307 . Registered January 18, 2017.
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    • Grant Information:
      20174Y0040 Shanghai Municipal Population and Family Planning Commission; 71804109 National Natural Science Foundation of China
    • Contributed Indexing:
      Keywords: Beliefs about medicines; Patient education and consulting; Satisfaction with medicines information; Systemic lupus erythematosus disease activity index
    • Molecular Sequence:
      ClinicalTrials.gov NCT03024307
    • Publication Date:
      Date Created: 20190615 Date Completed: 20190923 Latest Revision: 20260127
    • Publication Date:
      20260130
    • Accession Number:
      PMC6567412
    • Accession Number:
      10.1186/s12913-019-4206-y
    • Accession Number:
      31196083