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Two new quinochalcone glycosides from the safflower yellow pigments.

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  • Additional Information
    • Source:
      Publisher: Informa Healthcare Country of Publication: England NLM ID: 100888334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2213 (Electronic) Linking ISSN: 10286020 NLM ISO Abbreviation: J Asian Nat Prod Res Subsets: MEDLINE
    • Publication Information:
      Publication: London : Informa Healthcare
      Original Publication: [Newark, N.J.?] : Harwood Academic Publishers,
    • Subject Terms:
      Carthamus tinctorius* ; Chalcone*/analogs & derivatives; Animals ; Glycosides ; Mice ; Molecular Structure
    • Abstract:
      Two new quinochalcone glycosides, hydroxysafflor yellow A-4'- O - β -D-glucopyranoside ( 1 ) and 3'-hydroxyhydroxysafflor yellow A ( 2 ), were isolated from the safflower yellow pigments of Carthamus tinctorius . The structures of new compounds were elucidated by a detailed spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D NMR, ECD). The in vitro assay indicated that compound 1 could improve the survived rate of primary mouse cortical neurons on glutamate-induced neurons damage model at a concentration of 10 μM.
    • Contributed Indexing:
      Keywords: Carthamus tinctorius; 3'-hydroxyhydroxysafflor yellow A; Asteraceae; hydroxysafflor yellow A-4'-O-β-D-glucopyranoside; neuroprotective; quinochalcone glycosides; safflower yellow pigments
    • Accession Number:
      0 (Glycosides)
      1401-20-3 (safflower yellow)
      5S5A2Q39HX (Chalcone)
    • Publication Date:
      Date Created: 20201116 Date Completed: 20201126 Latest Revision: 20201126
    • Publication Date:
      20240513
    • Accession Number:
      10.1080/10286020.2020.1846530
    • Accession Number:
      33190510