Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection.

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Author(s): Kc R;Kc R; O'Toole RF; O'Toole RF
Source:
BMC research notes [BMC Res Notes] 2021 Apr 01; Vol. 14 (1), pp. 123. Date of Electronic Publication: 2021 Apr 01.
Publication Type:
Journal Article
Language:
English

Additional Information
- Source:
  Publisher: Biomed Central Country of Publication: England NLM ID: 101462768 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-0500 (Electronic) Linking ISSN: 17560500 NLM ISO Abbreviation: BMC Res Notes Subsets: MEDLINE
- Publication Information:
  Original Publication: London : Biomed Central, 2008.
- Subject Terms:
  Haemophilus Infections* ; Pulmonary Disease, Chronic Obstructive* ; Respiratory Tract Infections*; Australia ; Haemophilus influenzae/genetics ; Humans
- Abstract:
  Objectives: Nontypeable Haemophilus influenzae (NTHi) is an important human respiratory bacterium that can cause a range of diseases including sinusitis, otitis media, conjunctivitis, pneumonia as well as acute exacerbations of chronic obstructive pulmonary disease (COPD). A number of studies have used NTHi clinical isolate RHH-3 as a laboratory strain for experimentation examining the effect of cigarette smoke and more recently, biomass smoke, on the susceptibility and response of cells lining the respiratory tract to infection. Therefore, definition of the genome content of RHH-3 is required to fully elucidate human-NTHi interactions associated with initial infection and subsequent development of respiratory disease.
  Data Description: Here, we present the draft genome sequence of NTHi RHH-3 collected from the sputum of a patient at the Royal Hobart Hospital, Tasmania, Australia. The assembled genome size was 1,839,376 bp consisting of 61 contigs (> 500 bp), with a G+C content of 38.1%. This draft genome data can be accessed at DDBJ/ENA/GenBank under the accession number JADPRR000000000.
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- Contributed Indexing:
  Keywords: Chronic obstructive pulmonary disease; Nontypeable Haemophilus influenzae; Whole genome sequence
- Publication Date:
  Date Created: 20210402 Date Completed: 20210514 Latest Revision: 20220421
- Publication Date:
  20240513
- Accession Number:
  PMC8015102
- Accession Number:
  10.1186/s13104-021-05528-5
- Accession Number:
  33794985

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