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Epidemiological study in a small rural area of Veneto (Italian region) during Sars-Cov-2 Pandemia.

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  • Additional Information
    • Source:
      Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : Nature Publishing Group, copyright 2011-
    • Subject Terms:
    • Abstract:
      The emergence of severe acute respiratory syndrome type 2 coronavirus (SARS-CoV-2) and its complications have demonstrated the devastating impact of a new infectious pathogen. The organisational change promulgated by the isolation of affected communities is of extreme importance to achieve effective containment of the contagion and good patient care. The epidemiological study of the population of a small rural community in the North East of Italy revealed how much the virus had circulated during Spring, 2020, and how contagion has evolved after a prolonged lockdown. In the 1st phase, NAAT (Nucleic Acid Amplification Testing) was performed in cases with more or less severe symptoms and a study was performed to trace the infection of family members. Only 0.2% of the population tested positive on NAAT, via nasopharyngeal swab during this 1st phase. In the 2nd phase a random sample of the general population were tested for circulating anti-Sars-Cov-2 immunoglobulins. This showed that approximately 97.9% of the population were negative, while 2.1% (with positive IgG at a distance) of the population had contracted the virus in a mildly symptomatic or asymptomatic form. The main symptom in subjects who developed immunity was fever. Antibodies were found in subjects with forced coexistence with quarantined or infected subjects. The mutual spatial distance by categories has shown higher relative prevalence of IgG positive and IgM negative cases in close proximity but also far from the infected, with respect to an intermediate distance. This suggests that subjects living in thinly populated areas could come in contact with the virus more likely due to intentional/relational proximity, while those living nearby could also be infected through random proximity.
      (© 2021. The Author(s).)
    • References:
      Respirology. 2006 Jan;11(1):49-53. (PMID: 16423201)
      Euro Surveill. 2020 Nov;25(47):. (PMID: 33243356)
      N Engl J Med. 2020 Feb 20;382(8):727-733. (PMID: 31978945)
      J Infect Public Health. 2020 May;13(5):667-673. (PMID: 32340833)
      Lancet Public Health. 2020 May;5(5):e279-e288. (PMID: 32311320)
      Nat Rev Microbiol. 2021 Mar;19(3):171-183. (PMID: 33057203)
      J Epidemiol Community Health. 2021 Aug;75(8):729-734. (PMID: 33542030)
      N Engl J Med. 2020 Feb 20;382(8):692-694. (PMID: 31978293)
      Lancet. 2021 Mar 27;397(10280):1161-1163. (PMID: 33743219)
      JAMA Intern Med. 2020 Oct 1;180(10):1356-1362. (PMID: 32808970)
      PLoS One. 2021 Mar 29;16(3):e0249262. (PMID: 33780504)
      Int J Environ Res Public Health. 2020 May 08;17(9):. (PMID: 32397262)
      Microorganisms. 2020 Oct 31;8(11):. (PMID: 33142840)
      Gastroenterology. 2020 May;158(6):1518-1519. (PMID: 32142785)
      Immunity. 2020 May 19;52(5):737-741. (PMID: 32433946)
      J Clin Microbiol. 2020 May 26;58(6):. (PMID: 32245835)
      Front Med (Lausanne). 2020 Oct 30;7:564250. (PMID: 33195310)
      Emerg Microbes Infect. 2020 Dec;9(1):747-756. (PMID: 32196430)
      J Clin Pathol. 2020 Jul;73(7):370-377. (PMID: 32404473)
    • Accession Number:
      0 (Antibodies, Viral)
    • Publication Date:
      Date Created: 20211202 Date Completed: 20211213 Latest Revision: 20211214
    • Publication Date:
      20250114
    • Accession Number:
      PMC8636493
    • Accession Number:
      10.1038/s41598-021-02654-9
    • Accession Number:
      34853349