Serological and Molecular Evidence of the Circulation of the Venezuelan Equine Encephalitis Virus Subtype IIIA in Humans, Wild Vertebrates and Mosquitos in the Brazilian Amazon.

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Author(s): Silva FA;Silva FA;Silva FA; Ferreira MS; Ferreira MS; Araújo PA; Araújo PA; Casseb SMM; Casseb SMM; Silva SP; Silva SP; Nunes Neto JP; Nunes Neto JP; Chiang JO; Chiang JO; Rosa Junior JW; Rosa Junior JW; Chagas LL; Chagas LL; Freitas MNO; Freitas MNO; Santos ÉB; Santos ÉB; Hernández L; Hernández L; Paz T; Paz T; Vasconcelos PFC; Vasconcelos PFC; Vasconcelos PFC; Martins LC; Martins LC; Martins LC
Source:
Viruses [Viruses] 2022 Oct 28; Vol. 14 (11). Date of Electronic Publication: 2022 Oct 28.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
Language:
English

Additional Information
- Source:
  Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE
- Publication Information:
  Original Publication: Basel, Switzerland : MDPI
- Subject Terms:
  Encephalitis Virus, Venezuelan Equine*/genetics ; Culicidae* ; Arboviruses* ; Alphavirus*; Animals ; Humans ; Brazil/epidemiology ; Ecosystem ; Vertebrates
- Abstract:
  Understanding the interaction between viruses and ecosystems in areas with or without anthropic interference can contribute to the organization of public health services, as well as prevention and disease control. An arbovirus survey was conducted at Caxiuanã National Forest, Pará, Brazil, where 632 local residents, 338 vertebrates and 15,774 pools of hematophagous arthropods were investigated. Neutralization antibodies of the Venezuelan Equine Encephalitis virus, subtype IIIA, Mucambo virus (MUCV) were detected in 57.3% and 61.5% of humans and wild vertebrates, respectively; in addition, genomic fragments of MUCV were detected in pool of Uranotaenia (Ura.) geometrica . The obtained data suggest an enzootic circulation of MUCV in the area. Understanding the circulation of endemic and neglected arboviruses, such as MUCV, represents an important health problem for the local residents and for the people living in the nearby urban centers.
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- Contributed Indexing:
  Keywords: Mucambo virus; arbovirus; metagenomic
- Publication Date:
  Date Created: 20221111 Date Completed: 20221114 Latest Revision: 20230130
- Publication Date:
  20231215
- Accession Number:
  PMC9695375
- Accession Number:
  10.3390/v14112391
- Accession Number:
  36366489

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