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Hepatitis C virus prevalence among men who have sex with men: a cross-sectional study in 12 Brazilian cities.

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  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, [2001-
    • Subject Terms:
      HIV Infections*/epidemiology ; Sexual and Gender Minorities* ; Hepatitis C*/epidemiology ; Sexually Transmitted Diseases*/epidemiology; Male ; Humans ; Hepacivirus/genetics ; Homosexuality, Male ; Cross-Sectional Studies ; Brazil/epidemiology ; Cities/epidemiology ; Prevalence ; Risk Factors
    • Abstract:
      Background: Despite the preventive policies adopted, reduction in sexually transmitted infections (STIs) among men who have sex with men (MSM) has been limited. The risk of hepatitis C virus (HCV) infection has increased among the most vulnerable population groups, including MSM. The aim of this study was to estimate the prevalence of HCV infection and to assess risky practices among MSM from 12 Brazilian cities.
      Methods: This study was carried out from June to December 2016 using respondent driven sampling (RDS). Participants completed a self-administered questionnaire to collect behavioral, socioeconomic, and demographic variables. In addition, the rapid diagnostic test (RDT) for HCV was offered. Positive results were sent to Instituto Adolfo Lutz for confirmation.
      Results: A total of 4,176 participants were recruited and 23 samples were sent for confirmation. Of these, 16 were confirmed, resulting in a prevalence of 0.7% (95% CI: 0.3%-1.7%). The Southeast region showed a prevalence of 0.9% (95% CI: 0.3-2.6), followed by the South region, with 0.6% (95% CI: 0.2-2.1). The Northeast region had a prevalence of 0.3% (95% CI: 0.1-1.0) and the Midwest 0.1% (95% CI: 0.0-0.7). No positive cases were found in the North. Single men aged 40 years or older were the majority of participants exposed to HCV. High levels of alcohol consumption, illicit drug use, irregular condom use, in addition to infection with other STIs, were associated with exposure to HCV.
      Conclusions: STIs continue to be important health problems in Brazil and globally. Many STIs are inapparent for many years until they bring more serious consequences. Extra investment in HCV is also warranted, given that it can be eliminated. Relying solely on clinical data to provide information about inapparent infection, especially in stigmatized populations, will make that goal more difficult to achieve. Surveillance studies, such as the one reported here need to be repeated over time to demonstrate trends and to provide information for evaluation, program and policies. Investments in the most vulnerable populations are critical to achieve the World Health Organization global health goals including the elimination of viral hepatitis by 2030.
      (© 2023. BioMed Central Ltd., part of Springer Nature.)
    • References:
      Transfusion. 2020 Jan;60(1):106-116. (PMID: 31777096)
      BMC Public Health. 2010 Jun 07;10:317. (PMID: 20529289)
      J Clin Virol. 2017 Apr;89:1-4. (PMID: 28171829)
      Sex Transm Infect. 2015 Sep;91(6):430-3. (PMID: 25872512)
      Lancet Gastroenterol Hepatol. 2021 Jan;6(1):39-56. (PMID: 33217341)
      J Viral Hepat. 2014 Oct;21(10):696-705. (PMID: 25280229)
      Public Health Rep. 1998 Jun;113 Suppl 1:42-57. (PMID: 9722809)
      J R Stat Soc Ser A Stat Soc. 2015 Jan;178(1):241-269. (PMID: 27226702)
      AIDS Behav. 2008 Jul;12(4 Suppl):S97-104. (PMID: 18389357)
      Rev Bras Epidemiol. 2019 Mar 14;22:e190004. (PMID: 30892467)
      J Clin Microbiol. 2006 Jun;44(6):2051-6. (PMID: 16757597)
      Ann Intern Med. 2012 Dec 4;157(11):817-22. (PMID: 22910836)
      PLoS One. 2014 Aug 01;9(8):e102676. (PMID: 25083768)
      Lancet Gastroenterol Hepatol. 2022 May;7(5):396-415. (PMID: 35180382)
      Cad Saude Publica. 2011;27 Suppl 1:S4-5. (PMID: 21503523)
      PLoS One. 2020 Jul 15;15(7):e0235237. (PMID: 32667919)
      Sociol Methodol. 2010 Aug;40(1):285-327. (PMID: 22969167)
      Clin Microbiol Infect. 2011 Feb;17(2):107-15. (PMID: 21091831)
      PLoS Med. 2010 Aug;8(8):e1000444. (PMID: 21829329)
      Hepatology. 2005 Oct;42(4):962-73. (PMID: 16149085)
      Braz J Infect Dis. 2019 Jul - Aug;23(4):271-273. (PMID: 31344354)
      Cad Saude Publica. 2015 May;31(5):1035-48. (PMID: 26083178)
      PLoS One. 2009;4(3):e4997. (PMID: 19325707)
      J Clin Epidemiol. 2015 Dec;68(12):1463-71. (PMID: 26112433)
      Rev Assoc Med Bras (1992). 2011 Jan-Feb;57(1):107-12. (PMID: 21390467)
      Infect Drug Resist. 2021 Feb 24;14:723-730. (PMID: 33658809)
      BMC Infect Dis. 2013 Feb 01;13:60. (PMID: 23374914)
      Medicine (Baltimore). 2018 May;97(1S Suppl 1):S9-S15. (PMID: 29794604)
      Braz J Infect Dis. 2019 May - Jun;23(3):182-190. (PMID: 31145876)
      AIDS. 2013 Nov 13;27(17):2665-78. (PMID: 23842129)
      PLoS One. 2014 Feb 24;9(2):e89959. (PMID: 24587152)
      Braz J Med Biol Res. 2005 Jan;38(1):41-9. (PMID: 15665987)
      Epidemiology. 2012 Jan;23(1):148-50. (PMID: 22157310)
    • Grant Information:
      SCBA nº88881.689557/2022-0 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; #914BRZ1138 Ministério da Saúde
    • Contributed Indexing:
      Keywords: Brazil; Hepatitis C; RDS; Sexual and Gender Minorities
    • Publication Date:
      Date Created: 20231019 Date Completed: 20231023 Latest Revision: 20231123
    • Publication Date:
      20250114
    • Accession Number:
      PMC10588169
    • Accession Number:
      10.1186/s12879-023-08690-2
    • Accession Number:
      37858036