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Comorbidity risk and distribution characteristics of chronic diseases in the elderly population in China.

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  • Author(s): Xiang Z;Xiang Z; Wang H; Wang H; Li H; Li H
  • Source:
    BMC public health [BMC Public Health] 2024 Feb 03; Vol. 24 (1), pp. 360. Date of Electronic Publication: 2024 Feb 03.
  • Publication Type:
    Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968562 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2458 (Electronic) Linking ISSN: 14712458 NLM ISO Abbreviation: BMC Public Health Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, [2001-
    • Subject Terms:
      Diabetes Mellitus*/epidemiology ; Hypertension*/epidemiology ; Heart Diseases*/epidemiology ; Dyslipidemias*/epidemiology ; Lung Diseases*/epidemiology; Male ; Humans ; Female ; Aged ; Quality of Life ; Comorbidity ; Chronic Disease
    • Abstract:
      Background: The risk of comorbid chronic diseases in elderly people is an important problem affecting their health and quality of life. We analyzed the incidence of chronic diseases for combinations of chronic diseases analyzed.
      Methods: We used the original data to construct hypothetical cohorts of elderly individuals that evolved with age. The complex network was used to reduce the dimensionality of disease. The multistate transition model is used to calculate the incidence of each chronic disease, exploring comorbidity characteristics and rules.
      Results: (1) By using complex network, seven chronic diseases were screened out in men, including hypertension, diabetes, heart disease, stroke, chronic lung disease, arthritis and dyslipidemia; six chronic diseases in women showed significant comorbidity except chronic lung disease. (2) Incidence show differences in age and sex; incidence of chronic diseases generally increased with age. (3) The marginal risk increases with the number of basic chronic diseases associated with comorbidities. (4) When hypertension is present as a basic disease, its impact on the risk of other chronic diseases is much less than that of other chronic diseases. (5) When diseases occur as basic chronic diseases, hypertension-heart disease and diabetes-dyslipidemia are combinations that have the greatest impact on each other in men; hypertension-heart disease in women.
      Conclusions: The incidence of chronic diseases in patients who have chronic diseases and will form comorbidities differs from that in healthy states, and the related effects of different chronic diseases also differ. Among these conditions, hypertension is caused by a special mechanism.
      (© 2024. The Author(s).)
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    • Contributed Indexing:
      Keywords: Chronic diseases; Comorbidity risk; Complex network; Elderly; Multistate transition model
    • Publication Date:
      Date Created: 20240203 Date Completed: 20240205 Latest Revision: 20240209
    • Publication Date:
      20250114
    • Accession Number:
      PMC10837928
    • Accession Number:
      10.1186/s12889-024-17855-w
    • Accession Number:
      38310224