Severe lupus enteritis: A diagnostic and therapeutic enigma.

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Author(s): Singh N;Singh N; Janardhanan J; Janardhanan J; Kale S; Kale S; Krishnegowda J; Krishnegowda J; Kumar H; Kumar H; Naushad Ali SM; Naushad Ali SM; Arigela K; Arigela K; Ginigeri C; Ginigeri C; Bhattad S; Bhattad S
Source:
Lupus [Lupus] 2024 Nov; Vol. 33 (13), pp. 1483-1486. Date of Electronic Publication: 2024 Oct 03.
Publication Type:
Case Reports; Journal Article
Language:
English

Additional Information
- Source:
  Publisher: SAGE Publications Country of Publication: England NLM ID: 9204265 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0962 (Electronic) Linking ISSN: 09612033 NLM ISO Abbreviation: Lupus Subsets: MEDLINE
- Publication Information:
  Publication: London : SAGE Publications
  Original Publication: Houndmills, Basingstoke, Hampshire, UK : Scientific & Medical Division, Macmillan Press Ltd., c1991-
- Subject Terms:
  Enteritis*/diagnosis ; Enteritis*/drug therapy ; Enteritis*/etiology ; Lupus Erythematosus, Systemic*/complications ; Lupus Erythematosus, Systemic*/diagnosis ; Lupus Erythematosus, Systemic*/drug therapy ; Cyclophosphamide*/therapeutic use ; Methylprednisolone*/therapeutic use ; Methylprednisolone*/administration & dosage ; Lupus Nephritis*/diagnosis ; Lupus Nephritis*/drug therapy ; Lupus Nephritis*/complications; Humans ; Female ; Adolescent ; Immunosuppressive Agents/therapeutic use ; Pancreatitis/diagnosis ; Pancreatitis/etiology ; Vomiting/etiology ; Abdominal Pain/etiology ; Treatment Outcome
- Abstract:
  Lupus enteritis refers to the gastrointestinal involvement in systemic lupus erythematosus (SLE). It presents with diverse symptoms that frequently overlap with those of other acute abdominal conditions, posing diagnostic challenges. We describe an adolescent female, with lupus pancreatitis and nephritis, who later developed severe lupus enteritis during the course of her illness. She was treated with pulse methylprednisolone and intravenous cyclophosphamide and gradually improved over 3 weeks. Our case highlights the need to consider lupus enteritis in patients with severe pain abdomen and intractable vomiting. Presence of lupus pancreatitis and nephritis are risk factors for development of enteritis.
  Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Contributed Indexing:
  Keywords: Lupus enteritis; adolescent health; cyclophosphamide
- Accession Number:
  8N3DW7272P (Cyclophosphamide)
  X4W7ZR7023 (Methylprednisolone)
  0 (Immunosuppressive Agents)
- Publication Date:
  Date Created: 20241003 Date Completed: 20241016 Latest Revision: 20241016
- Publication Date:
  20250114
- Accession Number:
  10.1177/09612033241290579
- Accession Number:
  39361807

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Severe lupus enteritis: A diagnostic and therapeutic enigma.

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