Item request has been placed!
×
Item request cannot be made.
×
Processing Request
Perceived and endocrine acute and chronic stress indicators in fibromyalgia syndrome.
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
- Additional Information
- Source:
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
- Publication Information:
Original Publication: London : Nature Publishing Group, copyright 2011-
- Subject Terms:
- Abstract:
Fibromyalgia syndrome (FMS) is a chronic disorder characterized by widespread musculoskeletal pain, fatigue and tenderness and closely associated with high levels of stress. FMS is therefore often considered a stress-related disease. A comparative study was conducted with 99 individuals diagnosed with FMS and a control group of 50 pain-free individuals. Stress indicators were classified into three categories: perceived stress assessed using the Perceived Stress Scale, and daily average salivary cortisol and hair cortisol concentrations as indicators of acute and chronic stress levels related to the hypothalamic-pituitary-adrenal axis. Analysis of variance and covariance were used to identify group differences and the influence of covariates age, sex, and body mass index. Correlational analyses further elucidated the relationship between stress indicators and clinical symptoms. Participants with FMS reported significantly higher perceived stress levels than controls (p < .001, η p 2 = 0.3), which were positively correlated with symptom burden (r = .41, p < .001). In contrast, there were no significant differences in the endocrinological stress indicators salivary and hair cortisol between the groups (p > .05), nor were these indicators associated with clinical symptoms. The study highlights the central role of perceived stress in FMS, whereas endocrinological indicators did not differentiate FMS from controls. This finding calls for a nuanced approach to clinical assessment and therapeutic interventions tailored to patients with FMS, emphasizing the management of perceived stressors.
Competing Interests: Declarations. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s).)
- References:
Stress. 2012 Nov;15(6):578-88. (PMID: 22356099)
Pilot Feasibility Stud. 2022 Dec 9;8(1):251. (PMID: 36494768)
Int J Environ Res Public Health. 2018 Mar 07;15(3):. (PMID: 29518937)
Fam Pract. 2018 May 23;35(3):342-347. (PMID: 29145575)
Psychoneuroendocrinology. 2021 Nov;133:105391. (PMID: 34607270)
J Health Soc Behav. 1983 Dec;24(4):385-96. (PMID: 6668417)
Pain. 2019 Jan;160(1):28-37. (PMID: 30586068)
Arthritis Care Res (Hoboken). 2010 May;62(5):600-10. (PMID: 20461783)
Sci Rep. 2024 Feb 16;14(1):3947. (PMID: 38365860)
Psychoneuroendocrinology. 2020 Aug;118:104660. (PMID: 32485341)
Biol Psychol. 2011 May;87(2):183-94. (PMID: 21315796)
Arch Rheumatol. 2020 Jun 25;36(1):26-37. (PMID: 34046566)
J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jun 1;928:1-8. (PMID: 23584040)
J Biomed Inform. 2009 Apr;42(2):377-81. (PMID: 18929686)
Int J Health Sci (Qassim). 2021 Sep-Oct;15(5):46-59. (PMID: 34548863)
Psychoneuroendocrinology. 2005 Nov;30(10):1010-6. (PMID: 15950390)
Cochrane Database Syst Rev. 2020 Aug 12;8:CD007407. (PMID: 32794606)
PLoS One. 2018 Sep 13;13(9):e0203755. (PMID: 30212526)
Scand J Pain. 2019 Dec 18;20(1):77-86. (PMID: 31596726)
Brain Behav Immun. 2004 Jul;18(4):314-25. (PMID: 15157948)
Clin Exp Rheumatol. 2013 Nov-Dec;31(6 Suppl 79):S64-71. (PMID: 24143887)
Pain. 2023 Jul 1;164(7):1416-1427. (PMID: 36728497)
Arthritis Rheum. 2009 Jun 15;61(6):715-6. (PMID: 19479689)
Arch Gen Psychiatry. 2009 Jan;66(1):72-80. (PMID: 19124690)
Psychoneuroendocrinology. 2009 Jan;34(1):2-18. (PMID: 19041187)
Arthritis Rheum. 1990 Feb;33(2):160-72. (PMID: 2306288)
Brain Commun. 2023 Jul 05;5(4):fcad194. (PMID: 37465756)
J Rheumatol. 2011 Jun;38(6):1113-22. (PMID: 21285161)
J Clin Med. 2023 Mar 14;12(6):. (PMID: 36983246)
Psychosom Med. 2014 Jan;76(1):2-11. (PMID: 24336429)
Eur J Pain. 2024 May;28(5):821-830. (PMID: 38102835)
J Sports Sci Med. 2012 Dec 01;11(4):571-81. (PMID: 24150065)
JAMA Intern Med. 2014 Mar;174(3):399-407. (PMID: 24276929)
Sci Rep. 2024 Dec 16;14(1):30471. (PMID: 39681564)
Ann Clin Biochem. 2017 May;54(3):308-322. (PMID: 28068807)
Curr Rheumatol Rep. 2005 Oct;7(5):365-70. (PMID: 16174484)
Pain. 1985 Dec;23(4):345-356. (PMID: 4088697)
Nat Rev Rheumatol. 2023 Jan;19(1):44-60. (PMID: 36471023)
Int J Behav Med. 2010 Sep;17(3):223-33. (PMID: 20458566)
Diagnostics (Basel). 2021 Jan 03;11(1):. (PMID: 33401557)
Psychoneuroendocrinology. 2012 Feb;37(2):299-306. (PMID: 21764519)
Stress Health. 2024 Feb;40(1):e3285. (PMID: 37341705)
Clin Biochem. 2019 Jan;63:1-9. (PMID: 30261181)
J Rheumatol. 2015 Aug;42(8):1494-501. (PMID: 26077414)
Diagnostics (Basel). 2021 Jan 21;11(2):. (PMID: 33494476)
Sci Rep. 2021 Jan 14;11(1):1311. (PMID: 33446677)
Pain Med. 2019 Mar 1;20(3):464-475. (PMID: 29701812)
Psychoneuroendocrinology. 2016 Nov;73:148-156. (PMID: 27498290)
Psychophysiology. 2024 Nov;61(11):e14649. (PMID: 38984813)
Chronic Stress (Thousand Oaks). 2019 Jan-Dec;3:. (PMID: 31608312)
J Clin Invest. 2021 Jul 1;131(13):. (PMID: 34196305)
Semin Arthritis Rheum. 2016 Dec;46(3):319-329. (PMID: 27916278)
Neuroscience. 2016 Dec 3;338:114-129. (PMID: 27291641)
Open Rheumatol J. 2012;6:273-85. (PMID: 23002409)
Psychol Med. 2021 Jan;51(2):177-193. (PMID: 33602373)
Psychosom Med. 2018 Apr;80(3):317-326. (PMID: 29232329)
Psychoneuroendocrinology. 2017 Sep;83:25-41. (PMID: 28578301)
Rev Bras Reumatol Engl Ed. 2017 Jul - Aug;57(4):356-363. (PMID: 28743363)
Clin Rheumatol. 2016 Sep;35(9):2353-7. (PMID: 27245234)
Pain. 2022 Jul 1;163(7):1232-1253. (PMID: 34966131)
PLOS Glob Public Health. 2022 Aug 3;2(8):e0000571. (PMID: 36962547)
Arthritis Care Res (Hoboken). 2013 May;65(5):777-85. (PMID: 23424058)
Psychoneuroendocrinology. 2012 May;37(5):589-601. (PMID: 21974976)
J Psychiatr Res. 2022 Feb;146:77-82. (PMID: 34954363)
Psychother Psychosom. 2004 Sep-Oct;73(5):267-75. (PMID: 15292624)
BMB Rep. 2015 Apr;48(4):209-16. (PMID: 25560699)
Psychoneuroendocrinology. 2016 Jan;63:414-32. (PMID: 26563991)
J Pain Res. 2012;5:463-71. (PMID: 23152697)
Psychoneuroendocrinology. 2017 Mar;77:261-274. (PMID: 28135674)
- Contributed Indexing:
Keywords: Endocrine stress indicators; Fibromyalgia Syndrome; Perceived stress
- Accession Number:
WI4X0X7BPJ (Hydrocortisone)
- Publication Date:
Date Created: 20241216 Date Completed: 20241216 Latest Revision: 20250104
- Publication Date:
20250104
- Accession Number:
PMC11649902
- Accession Number:
10.1038/s41598-024-76635-z
- Accession Number:
39681564
No Comments.