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Effects of different acid etching protocols on the enhanced osteogenic potential of titanium surfaces: An in vitro study.

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  • Additional Information
    • Source:
      Publisher: Japanese Society for Dental Materials and Devices Country of Publication: Japan NLM ID: 8309299 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-1361 (Electronic) Linking ISSN: 02874547 NLM ISO Abbreviation: Dent Mater J Subsets: MEDLINE
    • Publication Information:
      Original Publication: Tokyo-to : Japanese Society for Dental Materials and Devices, [1982?-
    • Subject Terms:
      Titanium*/chemistry ; Acid Etching, Dental*/methods ; Osteogenesis*/drug effects; Surface Properties ; Cell Survival ; Materials Testing ; In Vitro Techniques ; Sulfuric Acids/chemistry ; Dental Implants ; Wettability ; Microscopy, Electron, Scanning ; Animals ; Osteoblasts ; Adsorption
    • Abstract:
      Sandblasted with large grits and acid-etched (SLA) surface topography has been a common method of implant surface modification to promote bone-implant integration in titanium-based dental implant manufacturing. However, the acid etching protocols used are various. The aim of this investigation was to validate the effect of different acid-etched treatments of sandblasted titanium surfaces on enhancing osteogenic potential. Five different titanium surface groups were prepared and tested including: i) smooth (Control), ii) sandblasted (SL), iii) sandblasted and acid-etched with H 2 SO 4 /HCl mixed solution (SLA/SOCl), iv) sandblasted and acid-etched with H 2 SO 4 solution (SLA/SO), and v) sandblasted and acid-etched with HF solution (SLA/HF). The surface characterization, protein adsorption, and cell behavior were examined to determine the osteogenic potential. Compared with the control group, other surface treated groups showed rougher surface, better wettability, more protein absorption, and cell viability, especially in the SLA/SOCl surface group. The results indicated that SLA surfaces prepared with H 2 SO 4 /HCl mixed acid solution provided significant potential to promote osteogenesis.
    • Contributed Indexing:
      Keywords: Acid etching; Osteogenesis; Sandblasting; Surface treatment; Titanium
    • Accession Number:
      D1JT611TNE (Titanium)
      O40UQP6WCF (sulfuric acid)
      0 (Sulfuric Acids)
      0 (Dental Implants)
    • Publication Date:
      Date Created: 20250429 Date Completed: 20250528 Latest Revision: 20250528
    • Publication Date:
      20250529
    • Accession Number:
      10.4012/dmj.2024-115
    • Accession Number:
      40301062