Skin burns after high-intensity focused ultrasound ablation: a retrospective control study.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Original Publication: London : Nature Publishing Group, copyright 2011-

High-Intensity Focused Ultrasound Ablation*/adverse effects ; Burns*/etiology ; Skin*/injuries; Humans ; Female ; Retrospective Studies ; Middle Aged ; Adult ; Risk Factors ; Aged ; Young Adult

Competing Interests: Declarations. Competing interests: The authors declare no competing interests.
High-intensity focused ultrasound (HIFU) ablation is a minimally invasive treatment for benign gynecological diseases, though skin burns remain a potential complication. Understanding risk factors is critical for improving safety. In this study, we aimed to investigate the risk factors for skin burns in patients who underwent HIFU ablation. This retrospective study included 229 patients who underwent HIFU ablation for benign gynecological diseases. The medical records of the included patients were retrospectively analyzed to identify risk factors for skin burns. The main outcome measure was the identification of the risk factors contributing to skin burns following HIFU ablation. Among the 229 included patients, 6 experienced skin burns following HIFU ablation. Multivariate regression analysis identified several factors associated with the occurrence of skin burns, including treatment duration, sonication time, focusing depth, and water sac use (P < 0.05). The duration of treatment and degree of skin compression are key factors that contribute to skin burns (P < 0.05). Shortening treatment duration, incorporating intraoperative cooling intervals, and limiting both compression duration and intensity significantly reduce skin burn incidence and improve patient outcomes.
(© 2025. The Author(s).)

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Keywords: Adenomyosis; Complication; High-intensity focused ultrasound; Skin burn; Uterine fibroids

Date Created: 20250801 Date Completed: 20250801 Latest Revision: 20250806

20250806

PMC12317018

10.1038/s41598-025-13436-y

40750815