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Tight Junction Proteins at the Crossroads of Inflammation, Barrier Function, and Disease Modulation.

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  • Author(s): Cha HJ;Cha HJ
  • Source:
    International journal of molecular sciences [Int J Mol Sci] 2025 Aug 22; Vol. 26 (17). Date of Electronic Publication: 2025 Aug 22.
  • Publication Type:
    Editorial; Introductory Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
    • Publication Information:
      Original Publication: Basel, Switzerland : MDPI, [2000-
    • Subject Terms:
      Inflammation*/metabolism ; Inflammation*/pathology ; Tight Junction Proteins*/metabolism ; Tight Junctions*/metabolism; Humans ; Animals
    • Abstract:
      Tight junctions (TJs), traditionally considered static structural elements sealing epithelial and endothelial monolayers, are now recognized as dynamic regulators of tissue homeostasis [...].
    • References:
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      Lancet Gastroenterol Hepatol. 2025 Jun;10(6):573-592. (PMID: 40086468)
      Tissue Barriers. 2015 Apr 03;3(1-2):e970936. (PMID: 25838978)
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      Gut. 2019 Mar;68(3):547-561. (PMID: 30297438)
      J Transl Med. 2023 Mar 31;21(1):233. (PMID: 37004099)
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      Histochem Cell Biol. 2008 Jul;130(1):55-70. (PMID: 18415116)
    • Accession Number:
      0 (Tight Junction Proteins)
    • Publication Date:
      Date Created: 20250913 Date Completed: 20250916 Latest Revision: 20250916
    • Publication Date:
      20260130
    • Accession Number:
      PMC12428315
    • Accession Number:
      10.3390/ijms26178115
    • Accession Number:
      40943041