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Correlation study of fatty pancreas and fatty liver CT manifestations with biochemical parameters in middle-aged and young adult cholecystectomy patients.

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  • Author(s): Zhou Y;Zhou Y; He C; He C; Zhang H; Zhang H
  • Source:
    BMC gastroenterology [BMC Gastroenterol] 2025 Nov 20; Vol. 25 (1), pp. 824. Date of Electronic Publication: 2025 Nov 20.
  • Publication Type:
    Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, [2001-
    • Subject Terms:
      Cholecystectomy*/adverse effects ; Fatty Liver*/epidemiology ; Fatty Liver*/diagnostic imaging ; Fatty Liver*/blood ; Fatty Liver*/etiology ; Pancreatic Diseases*/epidemiology ; Pancreatic Diseases*/diagnostic imaging ; Pancreatic Diseases*/etiology ; Pancreatic Diseases*/blood ; Postoperative Complications*/epidemiology; Blood Glucose/analysis ; Triglycerides/blood ; Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Adult ; Tomography, X-Ray Computed ; Incidence ; Young Adult
    • Abstract:
      Background: To investigate the correlation between the occurrence of pancreatic steatosis, hepatic steatosis, and cholecystectomy, as well as the associated biochemical parameters.
      Methods: A retrospective analysis was conducted on 409 patients who underwent abdominal CT scans between November 2022 and March 2024. Among them, 127 patients had undergone cholecystectomy (experimental group), while 282 had not (control group). The incidence rates of pancreatic steatosis and hepatic steatosis were compared between the two groups, along with relevant biochemical parameters including total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and fasting blood glucose levels.
      Results: The incidence of pancreatic steatosis in the experimental group was 67.8%, and the incidence of hepatic steatosis was 22%. In the control group, the incidence rates were 54.3% for pancreatic steatosis and 15.6% for hepatic steatosis. The rates of both pancreatic and hepatic steatosis significantly increased following cholecystectomy, with pancreatic steatosis showing a notably higher incidence than hepatic steatosis. Statistical analysis revealed a significant correlation between cholecystectomy and pancreatic steatosis (p < 0.05), whereas no significant correlation was found with hepatic steatosis.
      Conclusion: The incidence rates of both pancreatic and hepatic steatosis are elevated following cholecystectomy, particularly for pancreatic steatosis. The study indicates a significant association between cholecystectomy and pancreatic steatosis. Therefore, it is recommended to closely monitor patients who have undergone cholecystectomy for the development of pancreatic steatosis, allowing for early diagnosis and intervention to prevent the progression of related conditions.
      (© 2025. The Author(s).)
    • Abstract:
      Declarations. Ethics approval and consent to participate: This study was approved by the Ethics Committee of Shaanxi Provincial Hospital of Traditional Chinese medicine (AF/SC-04/0.01.2). Consent for publication: All authors approved the final manuscript and the submission to the journal. Competing interests: The authors declare no competing interests.
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    • Grant Information:
      2022B012 the Health Research Fund Project of Shaanxi Province
    • Contributed Indexing:
      Keywords: Biochemical parameters; CT manifestations; Cholecystectomy; Hepatic steatosis; Pancreatic steatosis
    • Accession Number:
      0 (Blood Glucose)
      0 (Triglycerides)
    • Publication Date:
      Date Created: 20251121 Date Completed: 20251121 Latest Revision: 20251123
    • Publication Date:
      20260130
    • Accession Number:
      PMC12636171
    • Accession Number:
      10.1186/s12876-025-04447-0
    • Accession Number:
      41267004