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Association of Hyponatremia on Mortality in Cryptococcal Meningitis: A Prospective Cohort

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  • Additional Information
    • Publication Information:
      Oxford University Press, 2022.
    • Publication Date:
      2022
    • Abstract:
      BACKGROUND: Sodium abnormalities are frequent in central nervous system infections and may be caused by cerebral salt wasting, syndrome of inappropriate antidiuretic hormone secretion, or medication adverse events. In cryptococcal meningitis (CM), the prevalence of baseline hyponatremia and whether hyponatremia adversely impacts survival is unknown. METHODS: We conducted a secondary analysis of data from 2 randomized trials of human immunodeficiency virus-infected adult Ugandans with CM. We grouped serum sodium into 3 categories
    • File Description:
      application/pdf
    • ISSN:
      2328-8957
    • Rights:
      OPEN
    • Accession Number:
      edsair.core.ac.uk....503e661c20f19b9c3b6163690e05820b