Associations of Long-Term Physical Activity Trajectories With All-Cause Mortality in a General Population

Objectives: We investigated the associations of mean levels of leisure-time physical activity (LTPA) and latent LTPA trajectories with all-cause mortality risk.Methods: Trajectories of LTPA were established using group-based trajectory analysis with a latent class growth model in a population-based cohort between 1996 and 2014. A Cox-proportional hazard model was conducted to examine the associations of LTPA quintiles and LTPA trajectories with all-cause mortality.Results: A total of 21,211 participants (age 18–90 years) were analyzed (median follow-up 16.8 years). The study participants were divided into five groups according to percentiles of LTPA (p = 0.031) or an increasing (HR 0.57, 95% CI 0.33–0.97, p = 0.037) trajectory had a significantly lower risk of all-cause mortality.Conclusion: Promotion of maintaining stable LTPA is beneficial for public health and survival.