Abstract: We review the in-medium modifications of effective masses (Lorentz scalar potentials or phenomenon of mass shift) of the heavy–heavy and heavy–light mesons in symmetric nuclear matter and their nuclear bound states. We use a combined approach with the quark–meson coupling (QMC) model and an effective Lagrangian. As demonstrated by the cases of pionic and kaonic atoms, studies of the meson–nucleus bound state can provide us with important information on chiral symmetry in a dense nuclear medium. In this review, we examine the mesons, K,K∗,D,D∗,B,B∗,η,η′,ϕ,ηc,J/ψ,ηb,Υ, and Bc, where our emphasis is on the heavy mesons. In addition, we also present some new results for the Bc-nucleus bound states.
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