Abstract: Aging is a phenomenon related to every person and has a tremendous impact on people’s life quality. During aging, some people may get neurodegenerative diseases, like Alzheimer’s disease. These diseases can vastly impair patient’s life quality and cause problems to their families. This review investigates and concludes many recent findings to find the symptoms, pathways, and possible cures for such diseases. The passage shows that changes happen at people’s gene, special protein function, and brain structure are closely related to such diseases. Consistent with such opinions, this review concludes what symptoms patients may have, such as Aβ’s accumulation and tau protein’s hyperphosphorylation, degeneration of basal ganglia. This review also focuses on the possible ways to cure the diseases or release their symptoms. At last, in light of the knowledge we have about neurodegenerative diseases, a more comprehensive understanding of the critical parts involved in these diseases can be obtained, indicating possibilities of producing more closely targeted medicine and treatment.
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