Usefulness of the delta neutrophil index to predict 30-day mortality in patients with ST segment elevation myocardial infarction

This study aimed to evaluate the association between the delta neutrophil index (DNI), which reflects immature granulocytes, and the severity of ST-elevation myocardial infarction (STEMI), as well as to determine the significance of the DNI as a prognostic marker for early mortality and other clinical outcomes in patients with STEMI who underwent reperfusion. This retrospective, observational cohort study was conducted using patients prospectively integrated in a critical pathway program for STEMI. We included 842 patients diagnosed with STEMI who underwent primary percutaneous coronary intervention (pPCI). Higher DNI values at time-I (within 2 h of pPCI; hazard ratio [HR], 1.075; 95% confidence interval [CI]: 1.046–1.108; p 2.5% at time-I (HR, 13.643; 95% CI: 8.13–22.897; p 2.9% at time-24 (HR, 12.752; 95% CI: 7.308–22.252; p